Evaluation of the antioxidant potential and phytochemical analysis of Terminalia mantaly and Terminalia ivorensis two plants of the Ivorian pharmacopoeia

Abstract

The neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis are characterized by a significant increase in oxidative stress that can lead to cellular damage to neurons. In recent years, the antioxidant activity of medicinal plants has become important in research against cancer and neurodegenerative diseases.
 Terminalia mantaly and Terminalia ivorensis are two plants traditionally used to treat lesions, wounds, ulcers and hemorrhoids, malaria and yellow fever. In the present work, we evaluated the antioxidant power and determined the secondary metabolites contained in these two plants.
 The results show that Terminalia mantaly and Terminalia ivorensis have a good antioxidant activity.
 They can be studied in the search for drugs against neurodegenerative diseases such as Alzheimer's disease.
 Keywords : Alzheimer's disease, Neurons, Parkinson's disease, Terminalia ivorensis and Terminalia mantaly

Season, storage and extraction method impact on the phytochemical profile of Terminalia ivorensis

“…Besides its economic usage, TI also serves as a good source of phytochemicals for ethno-medicinal purposes [ 9 ]. In in vitro studies, TI has been reported to show antibacterial, antifungal, antioxidant and anti-plasmodial effects [ 10 – 13 ]. Whereas several in vivo studies have found TI to possess anti-inflammatory, anti-nociceptive, anti-psychotic, hepatoprotective and nephroprotective properties in mice and rats [ 14 – 17 ].…”