2017
DOI: 10.7759/cureus.1422
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Abstract: ObjectiveTo evaluate the role of a transrectal ultrasound (TRUS) guided biopsy and a color Doppler test in the detection of prostate cancer in patients with increased serum prostate-specific antigen (PSA) levels and/or an abnormal digital rectal examination (DRE).MethodA total of 40 cases, ranging in age from 50 to 80 years and showing increased serum PSA levels (4-10 ng/ml) and/or abnormal DRE, were enrolled and underwent TRUS evaluation followed by color Doppler flowmetric studies. A TRUS-guided biopsy was p… Show more

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Cited by 8 publications
(9 citation statements)
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“…All patients, in the left lateral position, received TRUS examination by a skilled radiologist with 10 years of experience in prostate imaging. The TRUS exam was performed using the Aplio 500 (Toshiba Medical System Corporation, Tokyo, Japan) with a convex transducer (5)(6)(7)(8)(9)(10)(11)(12)(13)(14). The other radiologist with 15 years' experience in prostate biopsy performed a 12-core TRUS-SB, using an 18-gauge needle and automatic biopsy device (Biopty; Bard, Covington, GA) to perform biopsy cores.…”
Section: Conventional Ultrasonography Protocol and Biopsymentioning
confidence: 99%
See 1 more Smart Citation
“…All patients, in the left lateral position, received TRUS examination by a skilled radiologist with 10 years of experience in prostate imaging. The TRUS exam was performed using the Aplio 500 (Toshiba Medical System Corporation, Tokyo, Japan) with a convex transducer (5)(6)(7)(8)(9)(10)(11)(12)(13)(14). The other radiologist with 15 years' experience in prostate biopsy performed a 12-core TRUS-SB, using an 18-gauge needle and automatic biopsy device (Biopty; Bard, Covington, GA) to perform biopsy cores.…”
Section: Conventional Ultrasonography Protocol and Biopsymentioning
confidence: 99%
“…Researchers came up with a significant positive link between microvascularity and PCa back to 1993 (8). More experiment results demonstrated the feasibility of adding the blood flow information in predicting potential malignancy (9,10).…”
Section: Introductionmentioning
confidence: 99%
“…In 1983, Holm et al. initiated ultrasound (US)‐guided transperineal 125 I seed implantation for prostate cancer 7 . In 1987, Blasko et al 8 .…”
Section: Introductionmentioning
confidence: 99%
“…However, the sensitivity and specificity remain quite low due to the non-uniform characteristics of PCa on the conventional gray-scale ultrasound (US) images [3,4]. Previous studies applied color Doppler ultrasonography (CDUS) to improve the PCa detection rate [5,6], due to the association between angiogenesis and tumor growth [7]. CDUS measures the frequency shift in ultrasound waves as a function of blood velocity and direction, applying wall filtering to remove undesired slow blood flow signals that may be caused by slow, soft tissue motion [8].…”
Section: Introductionmentioning
confidence: 99%
“…The Gleason grading system is a cornerstone in the diagnosis and management of prostatic neoplasms since 1966 [14] with an update version in 2005 [15]. Increased CDUS blood flow signals tend to indicate more aggressive tumors with higher Gleason grading scores [16,17]. Despite the promising findings, we doubted over the efficiency of CDUS in evaluating corresponding Gleason scores and the sensitivity of PCa recognition, due to the limitation that low-velocity blood flow and small vessels are prone to color dropout.…”
Section: Introductionmentioning
confidence: 99%