volume 129, issue 1, P85-96 2004
DOI: 10.1016/j.chemphyslip.2003.12.005
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Abstract: Myeloperoxidase released from stimulated neutrophils is able to produce hypochlorous and hypobromous acids. The composition of the reaction products of the interaction of hypohalous acid with double bonds of phosphatidylcholines was analysed by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry using reagents enriched in 16O, 18O, 35Cl, 37Cl, 79Br, or 81Br. Two different types of products were assigned according to the mass spectra. First, chlorohydrins as well as bromohydrins were fo…

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