Evaluation of Preoperative Ultrasonographic and Biochemical Features of Patients With Aggressive Parathyroid Disease: Is There a Reliable Predictive Marker?

Abstract

ABSTRACTObjective: Parathyroid cancer (PC) represents < 1% of cases of PHPT. Tumors demonstrating atypical histopathologic features and don't fulfill criteria for carcinoma are classified as atypical adenomas (APA). The purpose of this study was to determine a biochemical or ultrasonographic feature that can predict aggressive disease requiring more extensive surgery and closer follow-up. Subjects and methods: Twenty eight patients operated for PHPT and diagnosed with atypical adenoma (23 patients) or carcino…