Evaluation of postoperative analgesia with intraperitoneal ropivacaine instillation in videolaparoscopic cholecystectomy

Albuquerque, Thiago Lucena César de; Bezerra, Monique Ferro; Schots, Cíntia Cibelly Paz Zuzu; Sohsten, Ana Karla Arraes Von; Amorim, Jane Auxiliadora; Filho, Otávio Damázio

doi:10.5935/1806-0013.20160027

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…With respect to the second dose of rescue analgesic required, we observed that in group R only 5 (16.6%) patients required second dose of rescue analgesic as compared to 13 (43.3%) in group B. Similar results were obtained in studies conducted by Albuquerque et al, 23 Porika et al 14 The findings of our study were also supported by a study conducted by Sharan et al 22 in which similar results were obtained with lesser number of patients requiring rescue analgesic with ropivacaine as compared to bupivacaine. VAS score was used to assess the quality of analgesia.…”

Section: Discussionsupporting

confidence: 90%

A Comparative Study of Intraperitoneal Ropivacaine and Bupivacaine for Postoperative Analgesia in Laparoscopic Cholecystectomy

Shrey¹,

Singam²,

Latwal³

et al. 2020

jemds

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BACKGROUND Every surgical procedure inflicts pain during the procedure which also continues in the post-operative period as post-operative pain. Intraperitoneal instillation of local anaesthetics in laparoscopic cholecystectomy has been used to reduce postoperative pain and to decrease the need for postoperative analgesics. We wanted to compare intraperitoneal instillation of bupivacaine and ropivacaine for postoperative analgesia in patients undergoing laparoscopic cholecystectomy. METHODS After obtaining ethical committee's clearance and informed consent, sixty patients, aged 20-60 years, of either gender, and American Society of Anaesthesiologists physical status I to II scheduled for laparoscopic cholecystectomy were included and categorized into two groups (n=30). Group B patients received 20 mL of 0.5% bupivacaine intraperitoneally after cholecystectomy and Group R patients received 20 mL of 0.75% ropivacaine intraperitoneally after cholecystectomy. Mean duration of postoperative analgesia and number of doses of rescue analgesic required were observed. Patients were assessed at 0, 2, 4, 8, 12, 18 and 24 hours postoperatively with respect to quality of analgesia (VAS), hemodynamic parameters and side effects. RESULTS Mean Time for first rescue analgesic requirement was 148.04 ± 53.47 min in group B and 295.38 ± 74.15 in group R and the difference was statistically significant (p=0.0001). In group R 17 (56.6%) patients did not require any rescue analgesic throughout the study period as compared to 8 (26.6%) patients in group B. The difference between the two groups was statistically significant. (p=0.019). A lower VAS score was observed in group R as compared to group B, with statistically significant difference at 2, 4 and 8 hours respectively. (p= 0.001, 0.003 and 0.032). CONCLUSIONS 0.75% ropivacaine is a better alternative to 0.5% bupivacaine when given intraperitoneally for management of postoperative pain in patients undergoing laparoscopic cholecystectomy under general anaesthesia as it prolongs the duration of analgesia, provides a better quality of analgesia till 8 hours postoperatively, with lesser demand and requirement of rescue analgesic in the postoperative period, and has lesser side effects.

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Section: Discussionsupporting

confidence: 90%

A Comparative Study of Intraperitoneal Ropivacaine and Bupivacaine for Postoperative Analgesia in Laparoscopic Cholecystectomy

Shrey¹,

Singam²,

Latwal³

et al. 2020

jemds

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“…The sample size was calculated based on the reduction of total dose of opioid consumption within the first postoperative 24 hours compared to baseline values by about 50% as in a previous similar study (11) (0.0301±0.04 versus 0.0639±0.04) mg kg -1 and the difference required a total sample size of 31 patients for each group to obtain 95 % power at a 5% significant level. The number of patients in each group was increased to 35 patients as drop out of 10% of patients was expected.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Gall Bladder Bed Infiltration on Analgesia in Laparoscopic Cholecystectomy

Sadek¹,

Baser²,

Mazy³

2020

jarss

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Objective: Gallbladder is highly innervated by parasympathetic and sympathetic nervous system through anterior and posterior hepatic plexus and the phrenic nerves. The aim of the current study is to evaluate the efficacy of infiltration of lidocaine into gallbladder bed in controlling postoperative abdominal pain and reducing analgesic consumption following laparoscopic cholecystectomy. Methods: This randomized prospective double-blind study was conducted on 70 patients applied for laparoscopic cholecystectomy. Six patients were excluded or dropped out and the patients were allocated into 2 groups as control group (n=32) in which gallbladder bed was infiltrated with normal saline and infiltration group (n=32) in which lidocaine was infiltrated into gallbladder bed. Pain within the first postoperative 24 hours, time to the need for first rescue analgesia and analgesic consumption were recorded. Results: The postoperative visual analogue score within the first 24 hour for visceral pain at rest, during coughing, and movement was significantly lower in the infiltration group than the control group, but it was similar for somatic pain. Time to first rescue analgesia was significantly longer in the infiltration than the control group. Significantly smaller number of patients required morphine and the total dose of postoperative analgesic consumption was lower in the infiltration than the control group. Conclusion: Gallbladder bed infiltration with lidocaine was associated with decreased visceral pain intensity at rest, coughing, and movement with reduced analgesic consumption in the first postoperative 24 hours.

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Pain Assessment and Autonomic Profile in Patients Undergoing Laparoscopic and Open Cholecystectomies: A Study of Respective Effects on Postoperative Pain

Guimarães,

Scassola,

Silva

et al. 2024

IFMBE Proceedings

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Evaluation of postoperative analgesia with intraperitoneal ropivacaine instillation in videolaparoscopic cholecystectomy

Cited by 3 publications

References 9 publications

A Comparative Study of Intraperitoneal Ropivacaine and Bupivacaine for Postoperative Analgesia in Laparoscopic Cholecystectomy

A Comparative Study of Intraperitoneal Ropivacaine and Bupivacaine for Postoperative Analgesia in Laparoscopic Cholecystectomy

The Effect of Gall Bladder Bed Infiltration on Analgesia in Laparoscopic Cholecystectomy

Pain Assessment and Autonomic Profile in Patients Undergoing Laparoscopic and Open Cholecystectomies: A Study of Respective Effects on Postoperative Pain

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