2015
DOI: 10.1111/jmp.12200
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Evaluation of ophthalmic and hemodynamic parameters in capuchin monkeys (Sapajus sp.) submitted to dissociative anesthetic protocols

Abstract: The established parameters may help in clinical and ophthalmic examinations of primates.

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Cited by 17 publications
(32 citation statements)
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References 33 publications
(62 reference statements)
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“…When analyzing the animals that received midazolam in comparison to the groups that received the alpha‐2 adrenergic agonist, lower values are seen in the latter. Such results comply with previous studies in humans and primates, in which the authors observed lower HR values for the animals that received the alpha‐2 adrenergic agonist in comparison with midazolam . When compared to the animals that received racemic and S(+) ketamine, no difference was seen between the groups.…”
Section: Discussionsupporting
confidence: 91%
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“…When analyzing the animals that received midazolam in comparison to the groups that received the alpha‐2 adrenergic agonist, lower values are seen in the latter. Such results comply with previous studies in humans and primates, in which the authors observed lower HR values for the animals that received the alpha‐2 adrenergic agonist in comparison with midazolam . When compared to the animals that received racemic and S(+) ketamine, no difference was seen between the groups.…”
Section: Discussionsupporting
confidence: 91%
“…Midazolam is used while combined with ketamine in primates, promoting excellent muscle relaxation with few side effects . It can be used to promote light sedation with muscle relaxation, with the objective of reducing stress and facilitating physical restraint, and it does not alter the heart rate (HR) and does not cause arrhythmia .…”
Section: Introductionmentioning
confidence: 99%
“…However, the animals were well below the arterial pressure necessary to remain in a surgical plane, whereas in the present study, a deeper anesthetic plane was needed to perform the laparotomy. The same results have been described with parenteral use of ketamine and DEX in capuchin monkeys . In contrast to the epidural use of DEX, analgesic doses of this drug do not have significant hemodynamic effects, such as hypotension, suggesting that reduction in the arterial pressure after epidural administration of DEX results from the α2 receptors' activation of sympathetic neurons present in the spinal cord …”
Section: Discussionsupporting
confidence: 73%
“…There were no significant changes in RR values, which remained within the physiological interval for the species in both groups . The decrease in RR commonly associated with opioids, especially total μ‐opioid receptor agonists such as MOR, was not observed in the MOR group with use of 0.1 mg/kg.…”
Section: Discussionmentioning
confidence: 77%
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