Evaluation of MWNT toxic effects on daphnia and zebrafish embryos

Olasagasti, Maider; Álvarez, Noelia; Vera, Carolina; Rainieri, Sandra

doi:10.1088/1742-6596/170/1/012018

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…Olasagasti et al [33] found that 16 mg/L carboxyl-functionalized MWNTs stabilized by Tween 20 (160 mg/L) caused 95% immobilization of D. magna after 48 h. Although the Tween 20 did not contribute to any immobilization (tested as a carrier control), no determination was available on its effects on particle size, surface chemistry, or toxicity when combined with MWNTs. They also found that exposure of 12 mg/L MWNTs stabilized by Tween 20 (160 mg/L) caused up to 45% mortality to Danio rerio embryos after 48 h. However, Tween 20 control caused 20% mortality after 48 h as well.…”

Section: Discussionmentioning

confidence: 99%

The influence of natural organic matter on the toxicity of multiwalled carbon nanotubes

Edgington

Roberts

Taylor

et al. 2010

Enviro Toxic and Chemistry

101

107

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Engineered carbon nanostructures, such as multiwalled carbon nanotubes (MWNTs), are inherently hydrophobic and are not readily stable in aqueous media. However, the aqueous stability and bioavailability of these nanotubes may be influenced by the water quality parameters such as ionic strength, pH, and natural organic matter (NOM). Natural organic matter adsorbs onto the surface of MWNTs, effectively covering the hydrophobic surface and resulting in increased aqueous stability. This enhanced stability is likely to lead to an increased residence time in the water column and increased exposure times for pelagic organisms. In the current study, NOM from three different river systems in the southeast United States increased the stability of MWNT suspensions. The effects of these suspensions were evaluated using acute and chronic bioassays with Daphnia magna and Ceriodaphnia dubia. The 96-h LC50 for D. magna exposed to MWNTs suspended in Suwannee River (USA) NOM was approximately 2.0 mg/L and was not significantly influenced by NOM concentrations ranging from 1.79 to 18.5 mg/L DOC. However, there were differences in 96-h LC50 values among different sources of NOM (Suwannee, Black, and Edisto Rivers, USA). Daphnid growth was reduced in both D. magna and C. dubia, whereas reproduction was reduced in C. dubia. Characterization of the different NOM sources and MWNT suspensions was conducted. Visual inspection using transmission electron microscopy (TEM) and gut elimination observations suggested that the toxicity was attributable to ingested MWNTs clogging the gut tract of D. magna. The TEM micrographs indicated that MWNTs can disaggregate within the gut tract, but single MWNTs are unable to absorb across the gut lumen.

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Section: Discussionmentioning

confidence: 99%

The influence of natural organic matter on the toxicity of multiwalled carbon nanotubes

Edgington

Roberts

Taylor

et al. 2010

Enviro Toxic and Chemistry

101

107

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“…Previous work on carbon-based MNMs demonstrated a need for a surfactant to establish a stable suspension. Many of the common surfactants (Tween 20 and isopropanol), however, have been demonstrated to be toxic toward sensitive aquatic organisms including D. magna (Olasagasti et al 2009). Bovine serum albumin has been proposed as a suitable dispersant for toxicity testing of MNMs because it has been demonstrated to have little to no adverse effects on test organisms.…”

Section: Discussionmentioning

confidence: 99%

Investigating the Impact of Manufacturing Processes on the Ecotoxicity of Carbon Nanofibers: A Multi–Aquatic Species Comparison

Barrick

Châtel

Manier

et al. 2019

Enviro Toxic and Chemistry

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Manufactured nanomaterial production is outpacing the ability to investigate environmental hazard using current regulatory paradigms, causing a backlog of materials requiring testing. To ameliorate this issue, regulatory bodies have proposed integrating safety into the production of novel nanomaterials, allowing for hazards to be identified early in development rather than aftermarket release. In addition, there is a growing interest in short‐term ecotoxicity testing to rapidly identify environmental hazards. In this sense, the present study investigated 3 carbon nanofibers (CNFs), created with different production methods, using short‐term in vitro and in vivo exposures on fish cell lines, mussel hemocytes, crustacea, and algae. The present study investigated if differences in ecotoxicity hazard between the CNFs could be identified and, if so, which product could be considered less hazardous. A major challenge in assessing the potential hazards posed by manufactured nanomaterials is standardizing the preparation for testing. Standardized operating protocols have been proposed using protein to facilitate the preparation of stable stock suspension, which is not environmentally representative. As such, the study also assessed the potential impacts these standardized protocols (with or without the use of protein) could have on the interpretation of environmental hazard. The results demonstrated that there were clear differences between the 3 CNFs and that the dispersion protocol influenced the interpretation of hazard, demonstrating a need for caution when interpreting ecotoxicity in a regulatory context. Environ Toxicol Chem 2019;38:2314–2325. © 2019 SETAC.

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A holistic study on potential toxic effects of carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) on zebrafish (Danio rerio) embryos/larvae

2019

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Evaluation of MWNT toxic effects on daphnia and zebrafish embryos

Cited by 3 publications

References 7 publications

The influence of natural organic matter on the toxicity of multiwalled carbon nanotubes

The influence of natural organic matter on the toxicity of multiwalled carbon nanotubes

Investigating the Impact of Manufacturing Processes on the Ecotoxicity of Carbon Nanofibers: A Multi–Aquatic Species Comparison

A holistic study on potential toxic effects of carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) on zebrafish (Danio rerio) embryos/larvae

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