Evaluation of Dietary Supplementation of Pleurotus Ostreatus and Calocybe Indica in Swiss Male Albino Mice

Abstract

Objective: The present study deals with dietary supplementation of Pleurotus ostreatus and Calocybe indica in Swiss male albino mice in comparison with casein control diet.Methods: The Swiss albino male mice were divided into four groups. Group 1 served as normal, Group II served as control mice, and Groups III and IV mice were fed with food supplement P. ostreatus and C. indica for 28 days. After 28 days, the animals were euthanized by cervical dislocation, and liver samples were used to analyze the following parameters such as superoxide dismutase (SOD), catalase, glutathione peroxidase, reduced glutathione (GSH), Vitamin C, and Vitamin E.Results: The results of the present study indicated that dietary supplementation of P. ostreatus and C. indica significantly (p<0.05) increased the antioxidants levels in experimental mice.Conclusion: From the results, it was found that the mushrooms such as P. ostreatus and C. indica seem to be a promising source because of its antioxidant properties. Therefore, this medicinal mushroom could be used as a nutritional supplementation for human.