2014
DOI: 10.1590/0037-8682-0140-2014
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Abstract: Introduction: Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have become common in hospitals and the community environment, and this wide resistance has limited patient treatment. Clindamycin (CL) represents an important alternative therapy for infections caused by S. aureus. Antimicrobial susceptibility testing using standard methods may not detect inducible CL resistance. This study was performed to detect the phenotypes of resistance to macrolides-lincosamides-streptogramin B (MLS B… Show more

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Cited by 25 publications
(33 citation statements)
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“…It was observed that percentage of inducible clindamycin resistance was higher among MRSA (22.58%) compared to MSSA (8.9%).This finding conforms to many published studies such as Gade et al, (2013), Majhi et al, (2016) and Lall et al, (2014). On the contrary, Sasirekha et al, (2014) and Bottega et al, (2014) had shown a higher percentage of inducible resistance in MSSA compared to MRSA. The different patterns of resistance observed in various studies are due to the fact that resistance varies by geographical regions, age groups, antibiotic prescription patterns, methicillin susceptibility and even from hospital to hospital.…”
Section: Resultssupporting
confidence: 86%
“…It was observed that percentage of inducible clindamycin resistance was higher among MRSA (22.58%) compared to MSSA (8.9%).This finding conforms to many published studies such as Gade et al, (2013), Majhi et al, (2016) and Lall et al, (2014). On the contrary, Sasirekha et al, (2014) and Bottega et al, (2014) had shown a higher percentage of inducible resistance in MSSA compared to MRSA. The different patterns of resistance observed in various studies are due to the fact that resistance varies by geographical regions, age groups, antibiotic prescription patterns, methicillin susceptibility and even from hospital to hospital.…”
Section: Resultssupporting
confidence: 86%
“…In different studies, the inducible clindamycin ranged from 0% to 37.1% [ Table 4 ]. [ 7 12 15 16 17 18 19 20 21 22 23 24 25 26 27 ] It was observed that percentage of inducible clindamycin resistance was higher among MRSA (24.8%) compared to MSSA (7.5%). The difference between MSSA and MRSA isolates were not statistically significant ( P = 0.2340).…”
Section: Discussionmentioning
confidence: 99%
“…The frequency of cMLS B and iMLS B of the present study was lower than those found in previous studies. Two other previous Brazil studies (Bottega et al, 2014;Pereira et al, 2016) have documented the rate of cMLS B and iMLS B in clinical MRSA strains ranging from 14.3 to 37.9% and 2.1 to 4.9%, respectively; while the KTG-R phenotype was not detected. In India, the MLS B phenotypes of MRSA in clinical samples were higher than those reported in this study.…”
Section: Antibiotic Profilesmentioning
confidence: 77%
“…However, the indiscriminate use of MLS B antibiotics has led to an increase in the number of Staphylococcus spp. strains that are resistant to these drugs (Bottega et al, 2014).…”
Section: Antibiotic Profilesmentioning
confidence: 99%