Evaluation of carotid intima-media thickness and factors associated with cardiovascular disease in children and adolescents with chronic kidney disease

Brachial-cuff excess pressure is associated with carotid intima-media thickness among Australian children: a cross-sectional population study

“…This may due to the narrow age range in the present study (11-12 years old), and that sex differences in the relationships with arterial physiology may not become apparent until around the age of 15 years. 23 The pubertal stage was negatively associated with carotid IMT among children, contrary to the finding of a recent study 29 . The reason for the inconsistency is unclear but may be due to the different sample size and population characteristics, as the prior study was performed in 55 children (9.2-14.8 years)…”

“…with chronic kidney disease 29 . The multivariable regression model with XSP fitted better than the similar model without XSP for estimating the association with carotid IMT, indicated by likelihood ratio.…”

Carotid Intima-Media Thickness in Children with Chronic Kidney Disease as an Early Predictor of Cardiovascular Diseases

“…Ziolkowska et al 22 reported a mean CIMT of 0.4±0.01mm (median 0.4; range 0.36-0.42) in patients, and the average CIMT in the control group was 0.41±0.01mm. We found slightly higher values of CIMT in contrast to Lopes et al 7 Likewise, no anomalous pulse wave velocity (PWV), was discovered, suggesting that there was no discernible variation in arterial stiffness among the research groups. In those with earlystage CKD, Sharifi et al 5 similarly showed that there was no meaningful association between the CIMT and paraclinical.…”

“…This test is used to evaluate the risk of cardiovascular disease and the degree of atherosclerosis. 5,6 Lopes et al 7 described that 74.5% of children and adolescents with CKD showed an increase in CIMT using ultrasonography techniques. Furthermore, a meta-analysis of 14 populations (cohort studies) revealed that for each 0.1 mm rise in CIMT, there was a 9% increase in the likelihood of developing cardiovascular disease (CVD).…”

A study on the relationship between serum uric acid and the thickness of intima-mediated carotid

“…Although half of the patients with normal CHD have LDLC, and the Tanaka study showed that the LDLC / HDLC ratio was able to predict myocardial infarction and sudden death when LDL is less than 120 mg/dl [25], and there is a significant relationship between CMIT and LDL in many studies [26], but in some studies, this relationship has not been seen [27] and it has more relationship with The lower HDL [27]. Lopes et al (2018) studied 55 patients with an average age of 11.9 years, suggesting a significant correlation with CIMT increase in chronic kidney disease and blood pressure as an independent factor [28]. However, the present study and most of the studies that have been done so far have been confronted with limitations, including the effects of genetic and nutritional differences between individuals, coincident diseases, methodological considerations, outcome measures, time of interventions, etc.…”