Evaluation of Carbon Dioxide Inhalation for Acute Focal Cerebral Infarction

Supportive Adrenocortical Steroid Therapy in Acute and Subacute Cerebrovascular Accidents, With Particular Reference to Brain‐stem Involvement

“…It does not increase the total cerebral blood flow (26). (The rebreathing of autogenous carbon dioxide by means of a paper bag, or the addition of 5 to 7 per cent carbon dioxide to oxygen inhaled by mask may be temporarily helpful in these instances because of increased cerebral blood flow (17, 27)).…”

Supportive Adrenocortical Steroid Therapy in Acute and Subacute Cerebrovascular Accidents, With Particular Reference to Brain‐stem Involvement

“…It does not increase the total cerebral blood flow (26). (The rebreathing of autogenous carbon dioxide by means of a paper bag, or the addition of 5 to 7 per cent carbon dioxide to oxygen inhaled by mask may be temporarily helpful in these instances because of increased cerebral blood flow (17, 27)).…”

Cerebral Circulatory Insufficiency

“…There is, however, little clinical evidence yet available that cerebral vasodilatators have any effect on minimizing areas of infarction. Thus the most potent cerebral vasodilatator-inhalation of 5 per cent carbon dioxide and 95 per cent oxygen-which is able to give a 75-100 per cent increase in cerebral blood flow, has no appreciable effect on the clinical course of brain infarction (Millikan 1955).…”

Treatment of progressing stroke.

“…18 ' " In hospitals where CAT scanning is available, the static brain scan in the differential diagnosis of progressing stroke is not useful.…”

“…The natural history of acute progressing stroke is quite variable which makes it desirable to compare treated and untreated patients. In 1955 18 204 consecutive patients with acute onset of progressing stroke believed to be due to disease in the carotid arterial system were reported. Within 2 weeks after onset, 12% of the patients were normal, 5% had some degree of monoparesis, 60% had some degree of hemiparesis and 14% died.…”

“…4 * Utilizing this great increase in cerebral blood flow following CO, inhalation, Millikan 18 studied its effect on acute focal cerebral infarction in 50 patients and compared them to 225 untreated patients. No statistically significant difference in the results in the 2 groups was found.…”

Supportive Adrenocortical Steroid Therapy in Acute and Subacute Cerebrovascular Accidents, With Particular Reference to Brain‐stem Involvement

“…It does not increase the total cerebral blood flow (26). (The rebreathing of autogenous carbon dioxide by means of a paper bag, or the addition of 5 to 7 per cent carbon dioxide to oxygen inhaled by mask may be temporarily helpful in these instances because of increased cerebral blood flow (17, 27)).…”

Cerebral Circulatory Insufficiency

“…There is, however, little clinical evidence yet available that cerebral vasodilatators have any effect on minimizing areas of infarction. Thus the most potent cerebral vasodilatator-inhalation of 5 per cent carbon dioxide and 95 per cent oxygen-which is able to give a 75-100 per cent increase in cerebral blood flow, has no appreciable effect on the clinical course of brain infarction (Millikan 1955).…”

Treatment of progressing stroke.

“…18 ' " In hospitals where CAT scanning is available, the static brain scan in the differential diagnosis of progressing stroke is not useful.…”

“…The natural history of acute progressing stroke is quite variable which makes it desirable to compare treated and untreated patients. In 1955 18 204 consecutive patients with acute onset of progressing stroke believed to be due to disease in the carotid arterial system were reported. Within 2 weeks after onset, 12% of the patients were normal, 5% had some degree of monoparesis, 60% had some degree of hemiparesis and 14% died.…”

“…4 * Utilizing this great increase in cerebral blood flow following CO, inhalation, Millikan 18 studied its effect on acute focal cerebral infarction in 50 patients and compared them to 225 untreated patients. No statistically significant difference in the results in the 2 groups was found.…”

Supportive Adrenocortical Steroid Therapy in Acute and Subacute Cerebrovascular Accidents, With Particular Reference to Brain‐stem Involvement

“…It does not increase the total cerebral blood flow (26). (The rebreathing of autogenous carbon dioxide by means of a paper bag, or the addition of 5 to 7 per cent carbon dioxide to oxygen inhaled by mask may be temporarily helpful in these instances because of increased cerebral blood flow (17, 27)).…”

Cerebral Circulatory Insufficiency

“…There is, however, little clinical evidence yet available that cerebral vasodilatators have any effect on minimizing areas of infarction. Thus the most potent cerebral vasodilatator-inhalation of 5 per cent carbon dioxide and 95 per cent oxygen-which is able to give a 75-100 per cent increase in cerebral blood flow, has no appreciable effect on the clinical course of brain infarction (Millikan 1955).…”

Treatment of progressing stroke.

“…18 ' " In hospitals where CAT scanning is available, the static brain scan in the differential diagnosis of progressing stroke is not useful.…”

“…The natural history of acute progressing stroke is quite variable which makes it desirable to compare treated and untreated patients. In 1955 18 204 consecutive patients with acute onset of progressing stroke believed to be due to disease in the carotid arterial system were reported. Within 2 weeks after onset, 12% of the patients were normal, 5% had some degree of monoparesis, 60% had some degree of hemiparesis and 14% died.…”

“…4 * Utilizing this great increase in cerebral blood flow following CO, inhalation, Millikan 18 studied its effect on acute focal cerebral infarction in 50 patients and compared them to 225 untreated patients. No statistically significant difference in the results in the 2 groups was found.…”