Evaluation of an enzyme immunoassay system for measuring herpes simplex virus (HSV) Type 1-specific and HSV Type 2-specific IgG antibodies

Performance of Focus ELISA tests for herpes simplex virus type 1 (HSV-1) and HSV-2 antibodies among women in ten diverse geographical locations

“…Finally, these data and those reported elsewhere [19,26] show that increasing the positive cut‐off to index values higher than 1.1 can increase specificity. A cut‐off of 3.5 increased the specificity for HSV‐2 to 96% (PPV 86%), but decreased the sensitivity to 90% (NPV 98%).…”

Performance of Focus ELISA tests for herpes simplex virus type 1 (HSV-1) and HSV-2 antibodies among women in ten diverse geographical locations

“…Finally, these data and those reported elsewhere [19,26] show that increasing the positive cut‐off to index values higher than 1.1 can increase specificity. A cut‐off of 3.5 increased the specificity for HSV‐2 to 96% (PPV 86%), but decreased the sensitivity to 90% (NPV 98%).…”

Effect of Sexually Transmitted Disease (STD) Coinfections on Performance of Three Commercially Available Immunosorbent Assays Used for Detection of Herpes Simplex Virus Type 2-Specific Antibody in Men Attending Baltimore, Maryland, STD Clinics

“…The Kalon and Focus immunoassays for HSV-2 performed well with samples from the high-prevalence African-American male population studied here, although the sensitivity of the Focus assay was much lower with this population than that noted previously (82.6% compared with 95 to 99%) (20,22).…”

Herpes simplex virus reactivation as a trigger of mucous lesions in pemphigus vulgaris

“…Serum samples were sequentially tested for the presence of HSV IgG antibody using an enzyme immunoassay . As shown in Table , the mean HSV IgG titres measured at the time of the initial presentation were significantly higher in patients with PV than in those with clinically apparent herpetic lesions, such as herpes labialis and EH.…”

Performance of Focus ELISA tests for herpes simplex virus type 1 (HSV-1) and HSV-2 antibodies among women in ten diverse geographical locations

“…Finally, these data and those reported elsewhere [19,26] show that increasing the positive cut‐off to index values higher than 1.1 can increase specificity. A cut‐off of 3.5 increased the specificity for HSV‐2 to 96% (PPV 86%), but decreased the sensitivity to 90% (NPV 98%).…”

Effect of Sexually Transmitted Disease (STD) Coinfections on Performance of Three Commercially Available Immunosorbent Assays Used for Detection of Herpes Simplex Virus Type 2-Specific Antibody in Men Attending Baltimore, Maryland, STD Clinics

“…The Kalon and Focus immunoassays for HSV-2 performed well with samples from the high-prevalence African-American male population studied here, although the sensitivity of the Focus assay was much lower with this population than that noted previously (82.6% compared with 95 to 99%) (20,22).…”

Herpes simplex virus reactivation as a trigger of mucous lesions in pemphigus vulgaris

“…Serum samples were sequentially tested for the presence of HSV IgG antibody using an enzyme immunoassay . As shown in Table , the mean HSV IgG titres measured at the time of the initial presentation were significantly higher in patients with PV than in those with clinically apparent herpetic lesions, such as herpes labialis and EH.…”

Performance of Focus ELISA tests for herpes simplex virus type 1 (HSV-1) and HSV-2 antibodies among women in ten diverse geographical locations

“…Finally, these data and those reported elsewhere [19,26] show that increasing the positive cut‐off to index values higher than 1.1 can increase specificity. A cut‐off of 3.5 increased the specificity for HSV‐2 to 96% (PPV 86%), but decreased the sensitivity to 90% (NPV 98%).…”

Effect of Sexually Transmitted Disease (STD) Coinfections on Performance of Three Commercially Available Immunosorbent Assays Used for Detection of Herpes Simplex Virus Type 2-Specific Antibody in Men Attending Baltimore, Maryland, STD Clinics

“…The Kalon and Focus immunoassays for HSV-2 performed well with samples from the high-prevalence African-American male population studied here, although the sensitivity of the Focus assay was much lower with this population than that noted previously (82.6% compared with 95 to 99%) (20,22).…”

Herpes simplex virus reactivation as a trigger of mucous lesions in pemphigus vulgaris

“…Serum samples were sequentially tested for the presence of HSV IgG antibody using an enzyme immunoassay . As shown in Table , the mean HSV IgG titres measured at the time of the initial presentation were significantly higher in patients with PV than in those with clinically apparent herpetic lesions, such as herpes labialis and EH.…”