1991
Evaluation of acrylic strips containing amoxycillin with clavulanic acid for local drug delivery
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“…Nakagawa et al (1991) using 2% minocycline-HCl ointment combined with SRP in patients with recurrent periodontal pockets have shown after 3 months, greater pocket reduction and elimination of perio-pathogenic microflora in these sites compared with sites treated with SRP alone. Several other antibiotics including amoxicillin with clavulanic acid (Abu Fanas et al 1991), metronidazole (Noyan et al 1997), azythromycin (Pradeep et al 2008) and niridazole (Barat et al 2006) were tested for local delivery in periodontal pockets with varying degrees of success.…”
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confidence: 99%