Evaluation of a protocol‐based intervention to promote timely switching from intravenous to oral paracetamol for post‐operative pain management: an interrupted time series analysis

Abstract

Following implementation, immediate decrease in utilisation and costs (p<0.05) and a trend change over the follow-up period were observed. Average monthly reduction was 26% (95%

Evaluation of pharmacist‐based interventions to optimise utilisation of parenteral paracetamol in a teaching hospital in Iran

“…The annual cost reduction by these strategies was estimated in that study to be £15 100 (equivalent to 5.8 trillion Iranian rials) . Similarly, another multifaceted, protocol‐based intervention to ensure timely switching from intravenous to oral paracetamol achieved a notable reduction in the utilisation and costs of PP in the first 5 months after its implementation …”

“…7 Similarly, another multifaceted, protocol-based intervention to ensure timely switching from intravenous to oral paracetamol achieved a notable reduction in the utilisation and costs of PP in the first 5 months after its implementation. 8 The success of evidence-based protocols in changing physicians' practise seems to depend on many factors, and improving the prescription of medicines through protocols requires both initial enforcement and continuous effort. It is now generally accepted that, in developing countries, protocols should be developed and implemented by the pharmacist for each level of care.…”

“…7 Another multifaceted protocol-based intervention with educational sessions for physicians before protocol implementation resulted in a marked reduction in PP administration and costs. 8 In addition, the mean number of vials used monthly decreased by 26% during the 12 months of follow-up after program implementation. 8 The primary objectives of the present cross-sectional interventional study were to clarify the appropriateness of PP prescription and evaluate the effects of a multifaceted intervention including educational and protocol interventions on decreasing the costs and inappropriate prescriptions of PP in a teaching hospital in Iran.…”

“…Another multifaceted protocol‐based intervention with educational sessions for physicians before protocol implementation resulted in a marked reduction in PP administration and costs . In addition, the mean number of vials used monthly decreased by 26% during the 12 months of follow‐up after program implementation …”

Strategies for reduction in the duration of intravenous drug use: Interest of drug tracers as quality indicators to improve intravenous to oral switch

“…This switch is usually well‐described for antimicrobials, as it is part of the antimicrobial stewardship programs . Several interventions have proven efficiency in promoting this switch, such as staff training, new documentation system, staff feedback, or new guidelines . It has also been reported that regular interventions, instead of a 1‐shot intervention, are necessary to get long‐lasting effect on IV to PO conversion …”