Evaluation of a New Fluoride-releasing One-step Adhesive

Abstract

INTRODUCTIONThe incidence and severity of secondary caries has been demonstrated to decrease around fluoridereleasing materials 1-6） . The use of composite resin restoration techniques has recently become an essential procedure in clinical dentistry, although it is not always possible to obtain a perfect marginal seal around the restoration. To overcome this problem, fluoride-releasing adhesive materials for composite resin restoratives have been introduced 7） . Fluoride-releasing adhesives are expected to show an inhibitory action against secondary caries, because the fluoride released should help to reduce the demineralization caused by enamel cracks or microleakage from the tooth-restoration interface 8,9） . It is noteworthy that many in vivo and in vitro studies have reported that fluoride-releasing restorative materials rendered the resin-enamel and resin-dentin interfaces more acid-resistant, thereby exerting a cariostatic effect 10-15） . Recently, a new type of self-etching agent, S-PRG （surface pre-reacted glass-ionomer） fillercontaining one-step adhesive （and thus fluoridecontaining）has been developed. Most importantly, it has received considerable acceptance due its simplified application procedure. Apart from this advantage, these products are expected to contribute effectively to inhibiting recurrent caries because being in direct contact with the tooth structure, they can act as a proximate reservoir of fluoride ions for uptake by enamel and dentin. However, the cariostatic activity of the newly developed adhesive is yet to be fully investigated.Therefore, the purpose of this in vitro study was to evaluate the S -PRG filler-containing one-step adhesive in terms of its fluoride release. In this connection, the uptake of released fluoride, as well as the acid resistance, of both enamel and dentin were also examined. MATERIALS AND METHODSThe fluoride-releasing and control one-step adhesives used in the study are indicated in Table 1. A nonfluoride-containing flowable composite resin FF （Filtek ® Flow, 3M, MN, USA）was used as the cavity filling material. The following investigations were then conducted. Fluoride releaseSpecimens were prepared using a plastic ring mold with an internal diameter of 9 mm and height of 1 mm. The molds with test materials were held between two glass slides and then covered with a transparent polyester strip. The materials were manipulated according to the manufacturers' instructions, and five specimens were prepared for each test ------------------------------------------------------In this study, a newly developed S-PRG（surface pre-reacted glass-ionomer）filler-containing one-step adhesive, called SI（SI-IB551, Prototype） , was evaluated regarding its fluoride release behavior. As a result, fluoride ion distribution in the tooth structures and acid resistance of cavity margins were also evaluated. In addition, Absolute ® （a fluoride-releasing one-step adhesive; AB）was evaluated in comparison to G-Bond ® （a non-fluoride-releasing one-step adhesive; GB）which was used ...

Obliteration of Dentinal Tubules by Desensitizing Agents Based on Silver Fluoride/Potassium Iodide or Pre-Reacted Glass Particles: An in Vitro Study

“…In agreement with other studies, we did not perform surface conditioning before applying the obliterating agents to simulate the presence of open dentinal tubules, a common situation in HD [12,19].…”

Obliteration of Dentinal Tubules by Desensitizing Agents Based on Silver Fluoride/Potassium Iodide or Pre-Reacted Glass Particles: An in Vitro Study

“…In agreement with other studies, we did not perform surface conditioning before applying the obliterating agents to simulate the presence of open dentinal tubules, a common situation in HD [12,19].…”

Influence of Different Mechanisms of Fluoride Release from Adhesive Systems

“…The principles of the present research protocol were based on the ASTM D 1179-10 standard (21). Nevertheless, the above-mentioned factors preclude direct comparison of fluoride release values from the present study with the values found in previous studies using the S-PRG-based adhesive (5,8).…”

Basic properties of novel S-PRG filler-containing cement

“…Replacement of hydroxyapatite in teeth with fluoroapatite and strontiumapatite is known to increase the acid resistance of the tooth structure 24) . In a previous study, S-PRG filler was found to aid fluoride uptake and increase the acid resistance zone in dentin 25) . In caries-affected dentine, the penetration depth of F − was 701 μm whereas that of B was 818 μm 26) .…”

Obliteration of Dentinal Tubules by Desensitizing Agents Based on Silver Fluoride/Potassium Iodide or Pre-Reacted Glass Particles: An in Vitro Study

“…In agreement with other studies, we did not perform surface conditioning before applying the obliterating agents to simulate the presence of open dentinal tubules, a common situation in HD [12,19].…”

Influence of Different Mechanisms of Fluoride Release from Adhesive Systems

“…The principles of the present research protocol were based on the ASTM D 1179-10 standard (21). Nevertheless, the above-mentioned factors preclude direct comparison of fluoride release values from the present study with the values found in previous studies using the S-PRG-based adhesive (5,8).…”

Basic properties of novel S-PRG filler-containing cement

“…Replacement of hydroxyapatite in teeth with fluoroapatite and strontiumapatite is known to increase the acid resistance of the tooth structure 24) . In a previous study, S-PRG filler was found to aid fluoride uptake and increase the acid resistance zone in dentin 25) . In caries-affected dentine, the penetration depth of F − was 701 μm whereas that of B was 818 μm 26) .…”

Obliteration of Dentinal Tubules by Desensitizing Agents Based on Silver Fluoride/Potassium Iodide or Pre-Reacted Glass Particles: An in Vitro Study

“…In agreement with other studies, we did not perform surface conditioning before applying the obliterating agents to simulate the presence of open dentinal tubules, a common situation in HD [12,19].…”

Influence of Different Mechanisms of Fluoride Release from Adhesive Systems

“…The principles of the present research protocol were based on the ASTM D 1179-10 standard (21). Nevertheless, the above-mentioned factors preclude direct comparison of fluoride release values from the present study with the values found in previous studies using the S-PRG-based adhesive (5,8).…”

Basic properties of novel S-PRG filler-containing cement

“…Replacement of hydroxyapatite in teeth with fluoroapatite and strontiumapatite is known to increase the acid resistance of the tooth structure 24) . In a previous study, S-PRG filler was found to aid fluoride uptake and increase the acid resistance zone in dentin 25) . In caries-affected dentine, the penetration depth of F − was 701 μm whereas that of B was 818 μm 26) .…”