Evaluation of a new dense-porous hydroxylapatite endosteal dental implant

Low temperature formation of calcium-deficient hydroxyapatite-PLA/PLGA composites

“…Previous works demonstrated that calcium-deficient hydroxyapatite of composition Ca 9 (HPO 4 )(PO 4 ) 5 OH with a Ca/P as low as 1.5 can be formed at physiological conditions, by acid-base type reactions between various calcium phosphate salts or hydrolysis of a calcium phosphate precursor, including ␣-tricalcium phosphate (␣-TCP). [2][3][4][5][6][7] The biocompatibility of HAp makes it very attractive for biomedical applications, including orthopedics, [8][9][10][11] dentistry, 12,13 and as a coating on metallic prostheses, 14,15 because it can develop a mechanically tight bond with bone. 16 Unfortunately, HAp monoliths are brittle, have low tensile strengths, low resistance to impact loading, and tend to fail when subjected to repeated loading.…”

Low temperature formation of calcium-deficient hydroxyapatite-PLA/PLGA composites

“…Previous works demonstrated that calcium-deficient hydroxyapatite of composition Ca 9 (HPO 4 )(PO 4 ) 5 OH with a Ca/P as low as 1.5 can be formed at physiological conditions, by acid-base type reactions between various calcium phosphate salts or hydrolysis of a calcium phosphate precursor, including ␣-tricalcium phosphate (␣-TCP). [2][3][4][5][6][7] The biocompatibility of HAp makes it very attractive for biomedical applications, including orthopedics, [8][9][10][11] dentistry, 12,13 and as a coating on metallic prostheses, 14,15 because it can develop a mechanically tight bond with bone. 16 Unfortunately, HAp monoliths are brittle, have low tensile strengths, low resistance to impact loading, and tend to fail when subjected to repeated loading.…”

Enthalpies of Formation of Compounds in the P2O5−CaO−H2O System

“…Associated with its biocompatibility, there is continuing interest in hydroxyapatite-based prostheses for applications involving orthopedics ,78 and dentistry. , There is, in addition, interest in coating the surfaces of metallic prostheses with hydroxyapatite as a means to promote bone intergrowth, thereby improving the bond between native tissue and prosthesis. , However, each of the applications enumerated has traditionally employed HAp prepared by high-temperature processing and shaping prior to its use. In scheduled procedures, where the use of HAp can be anticipated, the processing requirement may not be a disadvantage.…”

Low temperature formation of calcium-deficient hydroxyapatite-PLA/PLGA composites

“…Previous works demonstrated that calcium-deficient hydroxyapatite of composition Ca 9 (HPO 4 )(PO 4 ) 5 OH with a Ca/P as low as 1.5 can be formed at physiological conditions, by acid-base type reactions between various calcium phosphate salts or hydrolysis of a calcium phosphate precursor, including ␣-tricalcium phosphate (␣-TCP). [2][3][4][5][6][7] The biocompatibility of HAp makes it very attractive for biomedical applications, including orthopedics, [8][9][10][11] dentistry, 12,13 and as a coating on metallic prostheses, 14,15 because it can develop a mechanically tight bond with bone. 16 Unfortunately, HAp monoliths are brittle, have low tensile strengths, low resistance to impact loading, and tend to fail when subjected to repeated loading.…”

Enthalpies of Formation of Compounds in the P2O5−CaO−H2O System

“…Associated with its biocompatibility, there is continuing interest in hydroxyapatite-based prostheses for applications involving orthopedics ,78 and dentistry. , There is, in addition, interest in coating the surfaces of metallic prostheses with hydroxyapatite as a means to promote bone intergrowth, thereby improving the bond between native tissue and prosthesis. , However, each of the applications enumerated has traditionally employed HAp prepared by high-temperature processing and shaping prior to its use. In scheduled procedures, where the use of HAp can be anticipated, the processing requirement may not be a disadvantage.…”

Low temperature formation of calcium-deficient hydroxyapatite-PLA/PLGA composites

“…Previous works demonstrated that calcium-deficient hydroxyapatite of composition Ca 9 (HPO 4 )(PO 4 ) 5 OH with a Ca/P as low as 1.5 can be formed at physiological conditions, by acid-base type reactions between various calcium phosphate salts or hydrolysis of a calcium phosphate precursor, including ␣-tricalcium phosphate (␣-TCP). [2][3][4][5][6][7] The biocompatibility of HAp makes it very attractive for biomedical applications, including orthopedics, [8][9][10][11] dentistry, 12,13 and as a coating on metallic prostheses, 14,15 because it can develop a mechanically tight bond with bone. 16 Unfortunately, HAp monoliths are brittle, have low tensile strengths, low resistance to impact loading, and tend to fail when subjected to repeated loading.…”

Enthalpies of Formation of Compounds in the P2O5−CaO−H2O System

“…Associated with its biocompatibility, there is continuing interest in hydroxyapatite-based prostheses for applications involving orthopedics ,78 and dentistry. , There is, in addition, interest in coating the surfaces of metallic prostheses with hydroxyapatite as a means to promote bone intergrowth, thereby improving the bond between native tissue and prosthesis. , However, each of the applications enumerated has traditionally employed HAp prepared by high-temperature processing and shaping prior to its use. In scheduled procedures, where the use of HAp can be anticipated, the processing requirement may not be a disadvantage.…”