2005
DOI: 10.1017/s1481803500012859
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Etomidate and rapid sequence intubation

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“…[4][5][6][7] When compared with thiopental or propofol, etomidate would appear to be a less potent sedative, and can even cause seizure-like myoclonus at doses currently used. [8][9][10][11] This is corroborated from the experience reported in patients who are given etomidate alone for emergency intu-bation and for procedural sedation. [12][13][14][15][16] In patients given a paralytic, our work with the National Emergency Airway Registry has shown 3-fold lower odds of the clinically important outcome of successful first-pass intubation when etomidate is used when compared with more potent agents, after adjustment for operator experience and other factors.…”
supporting
confidence: 53%
“…[4][5][6][7] When compared with thiopental or propofol, etomidate would appear to be a less potent sedative, and can even cause seizure-like myoclonus at doses currently used. [8][9][10][11] This is corroborated from the experience reported in patients who are given etomidate alone for emergency intu-bation and for procedural sedation. [12][13][14][15][16] In patients given a paralytic, our work with the National Emergency Airway Registry has shown 3-fold lower odds of the clinically important outcome of successful first-pass intubation when etomidate is used when compared with more potent agents, after adjustment for operator experience and other factors.…”
supporting
confidence: 53%