Etnofarmacologia da Cuphea carthagenensis (Jacq.) J. F. Macbr: Uma revisão

Otênio, Joice Karina; Baisch, Rosselyn Gimenes; Carneiro, Vaneza Paula Poplawski; Lourenço, Emerson Luiz Botelho; Alberton, Odair; Jacomassi, Ezilda

doi:10.34117/bjdv6n3-048

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…One of the most studied folk medicinal Cuphea species is C. carthagenensis , known as Colombian waxweed. Whole plants or aerial parts are commonly used as antihypertensives [ 76 , 103 , 111 ]. The species is also an antinociceptive, antiviral, antimicrobial, anti-inflammatory, and weight-reducing agent [ 112 ].…”

Section: Pharmacological Activity Of Cuphea Plants...mentioning

confidence: 99%

The Genus Cuphea P. Browne as a Source of Biologically Active Phytochemicals for Pharmaceutical Application and Beyond—A Review

Sobolewska

Michalska

Wróbel‐Biedrawa

et al. 2023

IJMS

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Cuphea P. Browne (Lythraceae) is a monophyletic taxon comprising some 240–260 species that grow wild in the warm, temperate, and tropical regions of South and Central America and the southern part of North America. They have been valued as traditional medicinal remedies for numerous indications, including treating wounds, parasitic infections, hypertension, digestive disorders, cough, rheumatism, and pain. Modern pharmacological research provides data that support many of these traditional uses. Such a wide array of medicinal applications may be due to the exceptionally rich phytochemical profile of these plants, which includes bioactive compounds classified into various metabolite groups, such as polyphenols, triterpenes, alkaloids, and coumarins. Furthermore, Cuphea seed oils, containing medium-chain fatty acids, are of increasing interest in various industries as potential substitutes for coconut and palm oils. This review aims to summarize the results of phytochemical and pharmacological studies on Cuphea plants, with a particular focus on the therapeutic potential and molecular mechanisms of the action of polyphenolic compounds (especially flavonoids and tannins), which have been the subject of many recently published articles.

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Section: Pharmacological Activity Of Cuphea Plants...mentioning

confidence: 99%

The Genus Cuphea P. Browne as a Source of Biologically Active Phytochemicals for Pharmaceutical Application and Beyond—A Review

Sobolewska

Michalska

Wróbel‐Biedrawa

et al. 2023

IJMS

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“…J.F.Macbr. is indicated as a diaphortic, a diuretic, and a laxative (Otenio et al 2020), as well as for the control of arterial hypertension and prevention of arteriosclerosis (Lusa & Bona 2011). Lafoensia glyptocarpa Koehne, popularly known in the region as mirindiba-rosa, is ornamental (Souza & Lorenzi 2019).…”

Section: Introductionmentioning

confidence: 99%

Flora of Ceará, Brazil: Lythraceae

Silva,

Souza,

Sampaio

et al. 2023

Rodriguésia

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This study aimed to carry out a floristic-taxonomic survey of the Lythraceae representatives, as part of the project “Flora do Ceará: knowing to conserve”. The data were obtained via the morphologicals analysis of samples collected in the field, and collections in herbaria as well as in specialized bibliographies. In the state of Ceará, Lythraceae is represented by 15 species belonging to four genera: Ammannia (2); Cuphea (9), Lafoensia (3) and Pleurophora (1). The species were recorded in different phytophysiognomies, but they occur preferentially in the Steppic Savanna (Caatinga and/or Carrasco), in the Dense Ombrophilous Forest (Wet Forest) and in the Vegetation Complex of the Coastal Zone (Dunes and Lowland Semideciduous Forests). The taxon with the highest number of records was Cuphea campestris, which ocurrs in 26 municipalities. Eight species were recorded in ten conservation units in Ceará. Four species are endemic to the northeastern region: Cuphea campestris, C. laricoides, C. loefgrenii and Lafoensia glyptocarpa. Lafoensia glyptocarpa and L. pacari are new records for Ceará. The identification key, morphological descriptions, comments on distribution, ecology, phenology, uses, maps, and species illustrations are presented.

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“…Scientific interest in medicinal plants has proliferated recently due to increase efficacy of plant derived drugs, rising concerns about side effects of modern medicine and the continuing emergence of drug resistant organisms. These problems made the search for new drugs from novel sources necessary [2] as they are costly effective, available and sustainable [3,4].…”

Section: Introductionmentioning

confidence: 99%

Biochemical and Histopathological Effect of Detarium microcarpum Stem Bark Extract in Wistar Albino Rats

Mu’azu

Baba

Matinja

2020

AJRB

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Aim: In this study, the methanol stem bark extract of Detarium microcarpum was evaluated for sub-chronic, biochemical and histopathological studies. Methodology: Sub-chronic toxicity studies was investigated in rats administered with 35, 70 and 140 mg/kg doses of the extract orally for 28 days using standard laboratory procedures after the acute toxicity was carried out. Results: The median lethal dose (LD50) of the extract was calculated to be equal to (≥) 5000 mg/kg body weight in rats orally. Serological studies revealed significant (p<0.05) decrease in Alanine aminotransferase (ALT) at all doses tested, while at 140 mg/kg it caused a significant (p<0.05) increase in Alkaline Phosphatase (ALP). At doses of 70 and 140 mg/kg there was a significant (p<0.05) reduction in creatinine level. Histopathological studies on the liver showed moderate hepatocellular necrosis at doses of 35 and 70 mg/kg, while at 140 mg/kg there was intense hepatocellular necrosis, Kupffer cells and lymphocytes hyperplasia. The Kidney showed intense necrosis of tubules and glomerular necrosis with lymphocytes hyperplasia at all doses tested. The spleen also showed intense lymphocyte hyperplasia at all doses with sinusoidal congestion at the lowest dose of 35 mg/kg. The heart showed slight necrosis of cardiac muscle cells at all doses with blood congestion at 35 and 70mg/kg body weight. Conclusion: The study indicates that prolong use of the extract in the management of disease conditions may be associated with some adverse effect of some vital organs.

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Etnofarmacologia da Cuphea carthagenensis (Jacq.) J. F. Macbr: Uma revisão

Cited by 3 publications

References 8 publications

The Genus Cuphea P. Browne as a Source of Biologically Active Phytochemicals for Pharmaceutical Application and Beyond—A Review

The Genus Cuphea P. Browne as a Source of Biologically Active Phytochemicals for Pharmaceutical Application and Beyond—A Review

Flora of Ceará, Brazil: Lythraceae

Biochemical and Histopathological Effect of Detarium microcarpum Stem Bark Extract in Wistar Albino Rats

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