“…Hypo-and agammaglobulinaemic individuals usually respond well with delayed hypersensitivity reactions in spite of an almost total lack of plasma cells and ability to produce circulating antibodies (Perter , Kelly et al 1958, Aisenberg & Leskowitx 1963. On the other hand, patients with reticuloses such as sarcoidosis or Hodgkin's disease usually produce circulating antibodies normally while frequently failing to develop delayed hypersensitivity reactions ( Rostenberg 1951, Sokal & Primikirios 1961.…”