2011
DOI: 10.1590/s1516-44462011000500005 View full text |Buy / Rent full text
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Abstract: ResumoObjetivo: A depressão melancólica é um diagnóstico psiquiátrico de história de vida, geralmente com episódios recorrentes. Melancolia é uma síndrome com longa duração e características específicas de psicopatologia, insuficientemente diferenciada de depressão maior por um especificador no DSM-IV e parcialmente descrito nos critérios da Classificação Internacional de Doenças-10ª Edição. Dentro da classificação atual, é frequentemente vista em pacientes gravemente doentes com depressão e transtorno bipolar… Show more

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“…From the literature search on endocrine factors, a particular study demonstrated varied HPA axis function depending on severity of depression in humans [12]. Nandam et al demonstrated that the rate of the secretion of a specific hormone was altered in human patients with MDD [13].…”
Section: Resultsmentioning
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“…From the literature search on endocrine factors, a particular study demonstrated varied HPA axis function depending on severity of depression in humans [12]. Nandam et al demonstrated that the rate of the secretion of a specific hormone was altered in human patients with MDD [13].…”
Section: Resultsmentioning
“…The endocrine hypothesis displays a relation between the impacts of stress and the pathogenesis of MDD, through analysis of the HPA axis. This is because the HPA axis is one of the most important components in regulating homeostasis in response to stress [21]. Figure 1 displays the mechanism by which the HPA axis responds to stress.…”
Section: Endocrinementioning