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Cited by 7 publications
(8 citation statements)
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“…Further published data corroborated this lack of hypoglycaemic effect when an ethanolic extract of lyophilized C. sicyoides leaves was administered to normal rats submitted to dexamethasone treatment and a glucose‐tolerance test [16]. However, Silva et al [17] did not discard the possibility that excess blood glucose may be reduced by ingestion of an aqueous extract (tea), in view of the very large number of claims by diabetes patients that they control their symptoms tea, and this accords with our own results. The stimulatory effect that sulphonylureas have on β‐cells in the pancreas, to secrete more insulin, causes the blood glucose to be reduced even in healthy animals [18].…”
Section: Discussionsupporting
confidence: 90%
“…Silva et al [17] did not observe any hypoglycaemic effect when they gave crude aqueous alcohol extracts of lyophilized C. sicyoides prepared from dissicated leaves and stems, at 1.0 and 2.0 g/kg of body weight, to normal rats immediately after they had ingested 3 ml of 50% glucose solution. Further published data corroborated this lack of hypoglycaemic effect when an ethanolic extract of lyophilized C. sicyoides leaves was administered to normal rats submitted to dexamethasone treatment and a glucose‐tolerance test [16].…”
Section: Discussionmentioning
confidence: 88%
See 1 more Smart Citation
“…Silva et al (1996), Beltrame et al (2001), Beltrame et al (2002), Vasconcelos, (2004) e Lima (2007 não observaram essa atividade diferentemente de Mori et al (2001), Barbosa et al (2002), Pepato et al (2003) e Viana et al (2004).…”
Section: Resultsunclassified
“…As folhas são empregadas externamente contra reumatismo, abscessos e a infusão de folhas e do caule são utilizadas na infl amação muscular, na hipotensão e como ativadora da circulação sangüínea. A espécie em referência vem sendo muito empregada pela população para o tratamento do diabetes, sendo por isso conhecida como "insulina vegetal" dando motivo para estudos botânicos, químicos e farmacológicos no Brasil e no exterior (Silva et al, 1996;Mori et al, 2001;Beltrame et al, 2001;Pepato et al, 2003.…”
unclassified