2015
DOI: 10.1590/1983-084x/13_078
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Abstract: RESUMO Estudo experimental in vitro que objetivou investigar o potencial antimicrobiano e citotóxico de quatro frações e um extrato etanólico da espécie Pouteria venosa usada como planta medicinal. A atividade antimicrobiana foi determinada pelos testes de sensibilidade microbiana, como o método de difusão em disco e o método da microdiluição em caldo, para a determinação da Concentração Inibitória Mínima (CIM). Obteve-se a avaliação da citotoxicidade por meio do método colorimétrico do Metiltetrazolium. No es… Show more

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Cited by 4 publications
(5 citation statements)
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References 14 publications
(11 reference statements)
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“…An intriguing point is that all the samples of M. rufula showed considerable toxicity against THP-1-derived macrophages up to the concentration of 100 μg/mL. In the literature, the ethyl acetate fraction of Pouteria venosa (Sapotaceae) plant showed no toxicity on macrophages of the J774 lineage at the concentration of 200 μg/mL, which is in agreement with our results (Santos et al, 2015). Therefore, these preliminary data suggest that this plant possibly has low toxicity for application in in vivo models.…”
Section: IVsupporting
confidence: 92%
“…An intriguing point is that all the samples of M. rufula showed considerable toxicity against THP-1-derived macrophages up to the concentration of 100 μg/mL. In the literature, the ethyl acetate fraction of Pouteria venosa (Sapotaceae) plant showed no toxicity on macrophages of the J774 lineage at the concentration of 200 μg/mL, which is in agreement with our results (Santos et al, 2015). Therefore, these preliminary data suggest that this plant possibly has low toxicity for application in in vivo models.…”
Section: IVsupporting
confidence: 92%
“…They are also active in the P. aeruginosa strain, with an inhibition zone between (9 and 14 mm). The most promising fraction was the Ac-OEt of the stem bark, which is considered non-toxic and can be used in preclinical tests in vivo [32]. This study confirms that Pouteria venosa (Mart.)…”
Section: Research Using Four Types Of Plants Includingsupporting
confidence: 71%
“…Others species of Pouteria genus showed action against bacterial strains, including those tested in this study. The species P. venosa 36 , P. torta 37,38 , P. pallida and P. gardnerii 39,40 showed activity against S. aureus. The P. venosa 36 has an effect on S. epidermidis, and P. torta 37 , P. ramiflora, P. glomerata, P. psamophila and P. grandiflora 41 had antimicrobial action for E. coli.…”
Section: Discussionmentioning
confidence: 99%
“…The species P. venosa 36 , P. torta 37,38 , P. pallida and P. gardnerii 39,40 showed activity against S. aureus. The P. venosa 36 has an effect on S. epidermidis, and P. torta 37 , P. ramiflora, P. glomerata, P. psamophila and P. grandiflora 41 had antimicrobial action for E. coli. A recent study showed that strains of Klebsiella pneumoniae were the target of the inhibitory action of the P. caimito leaf extract.…”
Section: Discussionmentioning
confidence: 99%