Estudo das características epidemiológicas e clínicas de 332 casos de leishmaniose tegumentar notificados na região norte do Estado do Paraná de 1993 a 1998

Variables associated with the post-treatment healing of lesions in patients with American cutaneous leishmaniasis in Paraná State, Brazil

“…The majority of the patients studied were from the male working-class population, suggesting an extra-domi- Variables associated with the post-treatment healing of lesions 845 ciliary transmission of ACL, as was previously observed in the north of the state of Paraná (Silveira et al, 1999;Castro et al, 2002). However, the occurrence of cases in the age ranges of up to 15 and over 65 years, for both sexes, also suggests intra-or peri-domiciliary transmission occurred, corroborating data from the north of Paraná State (Roberto et al, 1997;Lima et al, 2002) and on an endemic area of the State of Minas Gerais, Brazil (Passos et al, 2001).…”

Clinical, laboratory, and therapeutic characteristics of American tegumentary leishmaniasis in the 15 th State Health Division, Northwest Paraná State, Southern Brazil

“…In the present study, ATL was predominant in males (85%) and in those aged ≥30 years (76.8%). In previous studies in Paraná State, Silveira et al (7) , Castro et al (8) , and Curti et al (14) reported a higher prevalence of ATL in patients aged 15-49 years, whereas Pontello et al (17) reported an associated age of 21-40 years. According to Silva et al (18) , the ATL incidence in individuals aged >65 years has increased significantly in Brazil.…”

“…The mucosal or mucocutaneous form of ATL is related to the prevalence of the L. (V.) braziliensis species in the North and Northwest regions of Paraná State (7) (8) . Of the cases reported in the 15 th RH Division, 16.8% were classified as mucosal or mucocutaneous form ATL.…”

“…This percentage is higher than that previously reported in the 15 th RH Division by Silveira et al (7) , who found 7.7% of cases with mucosal involvement from 1986 to 1997, by Curti et al (15) , who found 11.1% of cases with mucosal involvement from 1986 to 2005, and Roberto et al (16) , who found 9.7% of cases with mucosal or mucocutaneous involvement from 1991 to 1994. Castro et al (8) identified 2% of mucocutaneous lesions among patients in the Arapongas Regional Division of FUNASA (in Northern Paraná State) from 1993 to 1998, whereas Pontello et al (17) identified 15.1% of cases with mucosal involvement among patients in the 17 th RH Division (in Northern Paraná State) from 1998 to 2009. In Brazil, the Ministry of Health estimates that 3-5% of cutaneous cases develop into mucosal forms (13) .…”

“…Two circuits for ATL were identified in Paraná State: the Paraná-Paranapanema circuit, which highlights the Ivaí-Pirapó pole where the municipalities of the 15 th Regional Health Division are located, and the Ribeira circuit (6) . In the North and Northwest regions of Paraná State, Leishmania (Viannia) braziliensis is the prevalent species responsible for ATL (7) (8) . The clinical forms of L. (V.) braziliensis infection include cutaneous, mucosal, and disseminated leishmaniasis (9) .…”