Estudo da ozonioterapia como contribuição para a odontologia veterinária

Marques, Mariana Lage

doi:10.11606/d.10.2009.tde-17042009-161518

Cited by 5 publications

(9 citation statements)

References 45 publications

(123 reference statements)

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“…Ozone therapy increases tissue oxygenation, stimulates the production of endogenous antioxidants, and causes an immunosuppressive effect (with the stimulation of oxytocin release) in the circulatory system. 22 Ozone therapy acts by direct oxidation causing, for example, inactivation of microorganism or pain mediator and by activation of a nuclear effectors (Nrf2 or nuclear factor kappa B (NF-κB)) inducing a pharmacological response. 15 In low doses ozone stimulates cell protective pathways without altering cell viability 23 and ozone in high doses can be genotoxic.…”

Section: R Esultsmentioning

confidence: 99%

Ozonated oil in wound healing: what has already been proven?

2020

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Acute or chronic inflammatory reactions aim to control lesions, resist to pathogens attack and repair damaged tissue. The therapeutic administration of ozone known as ozone therapy appears as a possible treatment for tissue repair, as it promotes the healing of wounds. It has bactericidal, antiviral and antifungal properties and has been used as a therapeutic resource to treat inflammation. The objective was to carry out an integrative review regarding the use of ozonated oil in acute and chronic inflammations. The keywords “ozone therapy,” “inflammation” and “ozone” were used in the Portuguese, Spanish and English languages. The paper selection was based on inclusion and exclusion criteria. In total, 28 articles were selected. It has been seen that ozonated oil is effective in healing cutaneous wounds. The beneficial effects are due to the healing of wounds, due to the reduction of microbial infection, debridement effect, modulation of the inflammatory phase, stimulation to angiogenesis as well as biological and enzymatic reactions that favor the oxygen metabolism, improving the wound cicatrization. In addition to promoting healing, ozonated oil reduces symptoms related to skin burns, prevents post-lesion hyperpigmentation, and reduces the pain of aphthous ulcers. Therefore, ozonated oil represents an effective and inexpensive therapeutic alternative that must be implanted in the public health system.

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Section: R Esultsmentioning

confidence: 99%

Ozonated oil in wound healing: what has already been proven?

2020

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“…1,2 Therefore, the use of synergistic products as an adjuvant might enhance beneficial effects of the mechanical method. 1,[3][4][5] Ozone therapy is previously described in the prevention, control and treatment of periodontitis, as well as oral infections, due to its biocompatibility with epithelial and periodontal mucous cells. 6 Researchers refer to its effective use in dental procedures [6][7][8][9][10][11][12] considering its antimicrobial, [13][14][15] detoxification, 12 anti-inflammatory, analgesic, new vascularizing and immune stimulating action.…”

Section: Introductionmentioning

confidence: 99%

“…6 Researchers refer to its effective use in dental procedures [6][7][8][9][10][11][12] considering its antimicrobial, [13][14][15] detoxification, 12 anti-inflammatory, analgesic, new vascularizing and immune stimulating action. 3,8,16,17 Ozone toxicity is mainly related to the direct gas inhalation, 18,19 depending on its doses, frequency and antioxidant tissue capacity. 16 As a gas, it possesses a high molecular instability when diluted with water, turning into oxygen after a period of time.…”

Section: Introductionmentioning

confidence: 99%

“…1,2 Therefore, the use of synergistic products as an adjuvant might enhance beneficial effects of the mechanical method. 1,3 -5…”

Section: Introductionmentioning

confidence: 99%

“…6 Researchers refer to its effective use in dental procedures 6 -12 considering its antimicrobial, 13 -15 detoxification, 12 anti-inflammatory, analgesic, new vascularizing and immune stimulating action. 3,8,16,17…”

Section: Introductionmentioning

confidence: 99%

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Ozone Therapy in the Prevention of Dental Plaque Formation in Dogs

et al. 2021

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This study aims to assess ozonized mineral oil ointment application as an antiplaque therapy for dogs. Domestic healthy dogs received dental scaling and polishing under general anesthesia. Under standard feeding and homecare during 7 days, 20 dogs were randomly placed into 2 different groups for dental treatment. The control group (CG) was given a single placebo application and the ozone group (O3G) received daily ozonized ointment application. The average age (CG = 4.4; O3G = 5.7 years old), body weight (CG = 15.7; O3G = 15.3 kg) and the gingivitis index obtained on the first day (D0) allowed initial homogeneity between the groups. The dental plaque index, including clinical and computerized analysis on the seventh day, was obtained from the buccal aspect of specific dental locations. Both analyses revealed significant statistical association between daily application of ozone and antiplaque effect. There was no evidence of toxicity during the study. These results suggest that ozone therapy may be an efficient adjuvant to conventional periodontal treatment in decreasing initial dental plaque formation.

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Cisplatina e ozônio adjuvantes à exérese cirúrgica de carcinoma de células escamosas corneana em um equino

Carmo

nascimento

Cavalcante

et al. 2021

RSD

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O carcinoma de células escamosas (CCE) constitui uma neoplasia de epitélio escamoso que geralmente acomete as regiões da cabeça, orbital e genitais dos equinos. A irradiação solar é uma das principais causas, em especial nas áreas despigmentadas e desprovidas de pelos. O artigo a seguir relata o caso de um equino, macho, de 15 anos, que apresentou uma massa infiltrativa nodular por toda superfície corneana, sugerindo tecido de granulação aderido à córnea. Ao exame citológico a massa era indicativa de carcinoma de células escamosas. Inúmeras características medicinais do ozônio já são bastante reconhecidas e relatadas pela comunidade científica, entre elas: sua ação antioxidante, bactericida, fungicida, imunoestimulante, auxílio na cicatrização de feridas e atividade antitumoral. Visto isso, transcorreu-se a excisão cirúrgica, curetagem corneana, quimioterapia intralesional com utilização de cisplatina e ozonioterapia. O tratamento demonstrou que a excisão cirúrgica, associada ao uso de cisplatina e ozonioterapia no pós-cirúrgico, apresentaram resultados eficientes, com prognóstico favorável, visto que após dezoito meses da alta médica do animal, o proprietário não relatou recidiva.

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Estudo da ozonioterapia como contribuição para a odontologia veterinária

Cited by 5 publications

References 45 publications

Ozonated oil in wound healing: what has already been proven?

Ozonated oil in wound healing: what has already been proven?

Ozone Therapy in the Prevention of Dental Plaque Formation in Dogs

Cisplatina e ozônio adjuvantes à exérese cirúrgica de carcinoma de células escamosas corneana em um equino

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