2002
DOI: 10.1590/s0004-27302002000500010 View full text |Buy / Rent full text
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Abstract: RESUMOCom objetivo de analisar a freqüência de disfunção tiroideana e de identificar possíveis alterações hormonais decorrentes do envelhecimento, estudamos 198 indivíduos com idade variando de 50 a 85 anos e 106 filhos com idade entre 11 e 49 anos. A prevalência de disfunção tiroideana foi semelhante em ambos grupos (12,6% no grupo de estudo e 14,1% entre os filhos). A presença de um ou dois anticorpos antitiroideanos positivos foi também semelhante entre os grupos (9,1% e 12,3% para os idosos e filhos respec… Show more

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“…Among females, this maximal elevation occurred later, in the age group from 60 to 69 years. Similar variations were found in other studies 12,16,18,39 . The reduction in the mean and in the prevalence of high levels in individuals older than 70 years should be due to the longer survival of those without dyslipidemias 18 .…”
Section: Discussionsupporting
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“…Among females, this maximal elevation occurred later, in the age group from 60 to 69 years. Similar variations were found in other studies 12,16,18,39 . The reduction in the mean and in the prevalence of high levels in individuals older than 70 years should be due to the longer survival of those without dyslipidemias 18 .…”
Section: Discussionsupporting
“…Similar variations were found in other studies 12,16,18,39 . The reduction in the mean and in the prevalence of high levels in individuals older than 70 years should be due to the longer survival of those without dyslipidemias 18 . Comparing the sexes, the mean values were higher in males up to the fifth decade, but, from this age onwards, females had the higher levels.…”
Section: Discussionsupporting
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“…The 5.6% prevalence of hypothyroidism that we observed only reflects the prevalence of this disease in the general population, which is estimated to be between 2.3 and 10.3%. 28,29 On the other hand, the prevalence of hyperthyroidism in the general population ranges from 0.5 to 2.5%, 1,29,30 and thus is much lower than our findings, which underscores the possibility that hyperthyroidism is a cause or a trigger of atrial fibrillation in some patients. High prevalence of hyperthyroidism is characteristic of iodine-deficient regions, but this seems unlikely in our cases, because the Brazilian program of salt iodination has attained its goals over the last decade.…”
Section: Discussioncontrasting
“…It is possible that a number of patients evaluated in our study already have thyroid dysfunction, which could not be attributed to amiodarone use, because it was a cross-sectional study. Since the prevalence of thyroid dysfunction in the general population is low (16)(17)(18)(19)(20), the differences between our findings and the real ones should also be low. Transient abnormalities in thyroid hormone metabolism are usually observed during the first months of therapy with amiodarone (21).…”
Section: Discussioncontrasting