2002
DOI: 10.1001/jama.288.20.2539-jlt1127-1-3
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Estrogen Replacement Therapy and Risk of Ovarian Cancer in Postmenopausal Women—Reply

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Cited by 9 publications

(3 citation statements)
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“…However, there have been no clinical trials directly comparing tamoxifen and raloxifene. The results of the STAR (Study of Tamoxifen and Raloxifene) trials (47), in which postmenopausal women at increased risk for breast cancer are being randomly assigned to receive either tamoxifen or raloxifene for a 5-year period, are awaited with great interest.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…However, there have been no clinical trials directly comparing tamoxifen and raloxifene. The results of the STAR (Study of Tamoxifen and Raloxifene) trials (47), in which postmenopausal women at increased risk for breast cancer are being randomly assigned to receive either tamoxifen or raloxifene for a 5-year period, are awaited with great interest.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The use of hormone replacement therapy (HRT) recently was linked to an increased risk of ovarian cancer. Women who used estrogen-only therapy, especially those who used estrogen replacement for more than 10 years, were at significantly increased risk for developing ovarian cancer (Lacey et al, 2002). Additional studies evaluating the relationship between HRT and ovarian cancer risk have not been consistent.…”
Section: Hormone Replacement Therapymentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Evidence has accumulated from studies involving cell cultures, animal models, and epidemiology showing a strong linkage between exposure to estrogens and breast cancer risk [2,3]. Estrogens have also been found to be involved in colon cancer [4] and ovarian cancer, especially when connected to postmenopausal estrogen treatment [5,6].…”
Section: Introductionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.