Estrogen receptor status, adrenal androgens and 7α-hydroxydehydroepiandrosterone in breast cancer patients

The identification and simultaneous quantification of 7-hydroxylated metabolites of pregnenolone, dehydroepiandrosterone, 3β,17β-androstenediol, and testosterone in human serum using gas chromatography–mass spectrometry

“…To the best of our knowledge, no method for the simultaneous measurement of the serum 7-hydroxymetabolites of pregnenolone, DHEA, 3␤,17␤-androstendiol, and testosterone including the parent steroids has hitherto been reported. There is also no data available concerning the levels of 7-hydroxylated steroids in human serum beyond the studies of Skinner et al ( [42][43][44]), Attal et al ( [31]), and the authors' previous papers [29,30,32,40,45]. In all these latter cases, the measurements were limited to DHEA metabolites.…”

The identification and simultaneous quantification of 7-hydroxylated metabolites of pregnenolone, dehydroepiandrosterone, 3β,17β-androstenediol, and testosterone in human serum using gas chromatography–mass spectrometry

“…To the best of our knowledge, no method for the simultaneous measurement of the serum 7-hydroxymetabolites of pregnenolone, DHEA, 3␤,17␤-androstendiol, and testosterone including the parent steroids has hitherto been reported. There is also no data available concerning the levels of 7-hydroxylated steroids in human serum beyond the studies of Skinner et al ( [42][43][44]), Attal et al ( [31]), and the authors' previous papers [29,30,32,40,45]. In all these latter cases, the measurements were limited to DHEA metabolites.…”

The identification and simultaneous quantification of 7-hydroxylated metabolites of pregnenolone, dehydroepiandrosterone, 3β,17β-androstenediol, and testosterone in human serum using gas chromatography–mass spectrometry

“…To the best of our knowledge, no method for the simultaneous measurement of the serum 7-hydroxymetabolites of pregnenolone, DHEA, 3␤,17␤-androstendiol, and testosterone including the parent steroids has hitherto been reported. There is also no data available concerning the levels of 7-hydroxylated steroids in human serum beyond the studies of Skinner et al ( [42][43][44]), Attal et al ( [31]), and the authors' previous papers [29,30,32,40,45]. In all these latter cases, the measurements were limited to DHEA metabolites.…”

The identification and simultaneous quantification of 7-hydroxylated metabolites of pregnenolone, dehydroepiandrosterone, 3β,17β-androstenediol, and testosterone in human serum using gas chromatography–mass spectrometry

“…To the best of our knowledge, no method for the simultaneous measurement of the serum 7-hydroxymetabolites of pregnenolone, DHEA, 3␤,17␤-androstendiol, and testosterone including the parent steroids has hitherto been reported. There is also no data available concerning the levels of 7-hydroxylated steroids in human serum beyond the studies of Skinner et al ( [42][43][44]), Attal et al ( [31]), and the authors' previous papers [29,30,32,40,45]. In all these latter cases, the measurements were limited to DHEA metabolites.…”