Estimating mortality from coal workers' pneumoconiosis among Medicare beneficiaries with pneumoconiosis using binary regressions for spatially sparse data

Paul, Rajib; Adeyemi, Oluwaseun

doi:10.1002/ajim.23330

Cited by 7 publications

(3 citation statements)

References 29 publications

(73 reference statements)

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“…Comprehensive research conducted across the USA underscores that the prevalence of CWP and its most advanced manifestation, PMF, is notably higher in mines situated in the central Appalachian region. This conclusion is supported by data derived from the federal black lung program and the national surveillance database [31][32][33][34].…”

Section: Rcmd Sources and Exposure In Coal Minesmentioning

confidence: 70%

From Dust to Disease: A Review of Respirable Coal Mine Dust Lung Deposition and Advances in CFD Modeling

Madureira,

Aboelezz,

et al. 2023

Minerals

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The United States has witnessed a concerning surge in the incidence of diseases like Coal Workers’ Pneumoconiosis (CWP), despite numerous efforts aimed at prevention. This study delves into the realm of respiratory health by investigating the deposition of dust particles within the respiratory tract and lungs. By analyzing particles of varying sizes, shapes, velocities, and aerodynamic diameters, we aim to gain a comprehensive understanding of their impact on deposition patterns. This insight could potentially drive changes in dust exposure protocols within mining environments and improve monitoring practices. The interplay of several critical factors, including particle characteristics and an individual’s breathing patterns, plays a pivotal role in determining whether particles settle in the lungs or are exhaled. This paper provides a comprehensive literature review on Respirable Coal Mine Dust (RCMD), with a specific focus on examining particle deposition across different regions of the airway system and lungs. Additionally, we explore the utility of Computational Fluid Dynamics (CFD) in simulating particle behavior within the respiratory system. Predicting the precise behavior of dust particles within the respiratory airway poses a significant challenge. However, through numerical simulations, we aspire to enhance our understanding of strategies to mitigate total lung deposition by comprehensively modeling particle interactions within the respiratory system.

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Section: Rcmd Sources and Exposure In Coal Minesmentioning

confidence: 70%

From Dust to Disease: A Review of Respirable Coal Mine Dust Lung Deposition and Advances in CFD Modeling

Madureira,

Aboelezz,

et al. 2023

Minerals

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“…The prevalence of CAD among PCN has been presented by Paul et al, who collected information from 8531 patients with PCN from the 5% Medicare Claims Limited Data Set in the United States between 2011 and 2014 [ 5 ]. They reported that CAD occurred in 13.9% of all patients with PCN and accounted for 18.7% of those who lost their lives.…”

Section: Discussionmentioning

confidence: 99%

“…Various kinds of mineral dust could cause various respiratory and cardiovascular diseases. PCN is associated with poor prognosis from these diseases [ 3 , 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Risk of Acute Myocardial Infarction in Pneumoconiosis: Results from a Retrospective Cohort Study

et al. 2023

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Background: Pneumoconiosis (PCN) has several comorbidities, most notably pulmonary and cardiovascular diseases. However, much is still unknown about the relationship between PCN and acute myocardial infarction (AMI). The present study aimed to clarify the association between PCN and subsequent AMI risk using a retrospective cohort study design. Methods: This was a population-based, retrospective cohort study that used data from Taiwan’s National Health Insurance Database. A total of 7556 newly diagnosed patients with PCN and 7556 individuals without PCN were included in the PCN and comparison cohort (PC and CC), respectively, between 2008 and 2018, with propensity score matching for age, gender, comorbidity, medication, and date of PCN diagnosis. The occurrence of AMI was monitored until the end of 2019, and AMI risk was assessed using Cox proportional hazard regression models. Results: The overall incidence of AMI was 1.34-fold higher in the PC than in the CC (4.33 vs. 3.23 per 1000 person-years, respectively, p < 0.05), with an adjusted hazard ratio (aHR) of 1.36 (95% confidence interval (CI): 1.08–1.72) after controlling for age, gender, comorbidity, and medication. Further analyses showed a higher risk of AMI with increased annual number of emergency department visits among patients with PCN (aHR: 1.30, 95% CI: 1.01–1.66 (<1) and aHR: 1.68, 95% CI: 1.13–2.50 (≥1)). Conclusion: Patients with PCN had a significantly higher risk of developing AMI than those without PCN. Clinicians should pay more attention to prevent AMI episodes in patients with PCN.

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Estimating mortality from coal workers' pneumoconiosis among Medicare beneficiaries with pneumoconiosis using binary regressions for spatially sparse data

Paul

Adeyemi

2022

American J Industrial Med

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Background: Coal workers' pneumoconiosis (CWP) is an occupational lung disease due to inhalation of coal dust. We estimated mortality from CWP and other pneumoconioses among Medicare beneficiaries.Methods: We used the 5% Medicare Limited Claims Data Set, 2011-2014, to identify patients diagnosed with ICD-9-CM 500 (CWP) through 505 (Asbestosis, Pneumoconiosis due to other silica or silicates, Pneumoconiosis due to other inorganic dust, Pneumonopathy due to inhalation of other dust, and Pneumoconiosis, unspecified) codes. We applied binary regression models with spatial random effects to determine the association between CWP and mortality. Our inferences are based on Bayesian spatial hierarchical models, and model fitting was performed using Integrated Nested Laplace Approximation (INLA) algorithm in R/RStudio software. Results:The median age of the sample was 76 years. In a sample of 8531 Medicare beneficiaries, 2568 died. Medicare beneficiaries with CWP had 25% higher odds of death (adjusted OR: 1.25, 95% CI: 1.07, 1.46) than those with other types of pneumoconiosis. The number of comorbid conditions elevated the odds of death by 10% (adjusted OR: 1.10, 95% CI: 1.09, 1.10). Conclusion: CWP increases the likelihood of death among Medicare beneficiaries.Healthcare professionals should make concerted efforts to monitor patients with CWP to prevent premature mortality.

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Estimating mortality from coal workers' pneumoconiosis among Medicare beneficiaries with pneumoconiosis using binary regressions for spatially sparse data

Cited by 7 publications

References 29 publications

From Dust to Disease: A Review of Respirable Coal Mine Dust Lung Deposition and Advances in CFD Modeling

From Dust to Disease: A Review of Respirable Coal Mine Dust Lung Deposition and Advances in CFD Modeling

Risk of Acute Myocardial Infarction in Pneumoconiosis: Results from a Retrospective Cohort Study

Estimating mortality from coal workers' pneumoconiosis among Medicare beneficiaries with pneumoconiosis using binary regressions for spatially sparse data

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