“…5 Oral isotretinoin can help with keratotic papules and local pigmentation, but its efficacy on facial telangiectasia is limited, and recurrence often occurs shortly after treatment cessation. 1,7,8 Many patients find the most troublesome symptoms to be facial/neck flushing or redness, particularly in response to sunlight exposure, enclosed spaces, or emotional fluctuations. These symptoms tend to worsen over time.…”