Erythrocytic oxidative damage in crossbred cattle naturally infected with Babesia bigemina

Status of lipid peroxidation and antioxidant enzymes in goats naturally infected with Babesia ovis

“…For evaluation of MDA and estimation of antioxidant enzymes, blood samples were centrifuged at 700 × g for 15 min, plasma was separated and packed cells were washed three times with a normal saline solution (0.9%). The washed erythrocytes were then hemolysed with nine volumes of ice-cold distilled water to prepare 10% RBC hemolysate (Saleh 2009). Bijan Esmaeilnejad et al 230 …”

“…It is markedly increased at the onset of anemia in natural B. bigemina infections and an inverse relationship has been observed between methemoglobin levels and the PCV (Saleh 2009). In B. gibsoni infections, there is strong evidence of the role of erythrocyte oxidation *Corresponding author: mtavassoli2000@yahoo.com Evaluation of antioxidant status and oxidative stress in goats infected with B. ovis 229 (as indicated by lipid peroxidation, hemoglobin oxidation and increased osmotic fragility of erythrocytes) in the pathogenesis of anemia observed in infected dogs (Otsuko et al 2001, Kumar et al 2006, Chaudhuri et al 2008.…”

“…B. ovis is considered as a highly pathogen organism which caused small ruminats' babesiosis in most part of Iran (Rahbari et al 2008). The main feature of the disease is hemolytic anemia (Habibi et al 2004, Sevinc et al 2007, caused by mechanical damage (Callow and Pepper 1974), autoimmune phenomena (Argon 1976), increase of host erythrocyte permeability (Alkhalil et al 2007) and erythrophagocytosis by activated macrophage (Saleh 2009). …”

Babesiosisli Koyunlarda Plazma Malondialdehid, Tiroid Hormonları ve Bazı Kan Profilleri

“…Anemia results from the physical effects on erythrocytes, activated macrophage-mediated erythrocyte phagocytosis, antibodyaffected erythrocytes and enhanced cell membrane permeability 7 . Moreover, severe cases are not always accompanied by parasitemia 6 , while non-parasitic factors may also destroy erythrocytes in animals with parasite infections.…”

“…Moreover, severe cases are not always accompanied by parasitemia 6 , while non-parasitic factors may also destroy erythrocytes in animals with parasite infections. Free radicals are thought to play a role in erythrocyte demolition; the assessment of free radicals in the pathogenesis of parasitic infections garnered increasing attention in recent years [7][8][9][10] .…”