“…The cases of Wong et al [8] and Ter Poorten and Sharbaugh [7] are somehow re lated to our case. The first one concerns a 6-year-old girl, who had 5 CEM, and the se cond one a 10-year-old girl, who had had for approximately 3 months an atypical CEM on the right cheek, from which spontaneous extrusion of granular calcified material was noted.…”
A very rare case of calcifying epithelioma of Malherbe (CEM) with a rapid evolution and perforation of the epidermis is reported. Clinical appearance was atypical and did not suggest any diagnosis. Histopathologic examination shows a picture of CEM with some peculiar findings. Furthermore, in the upper dermis there are epithelial strands of shadow cells, partially calcified, tending to come in contact with the perforated epidermis and to be eliminated through it. The acute form of CEM and the mechanism of epidermal perforation in perforating dermatoses are discussed.
“…The cases of Wong et al [8] and Ter Poorten and Sharbaugh [7] are somehow re lated to our case. The first one concerns a 6-year-old girl, who had 5 CEM, and the se cond one a 10-year-old girl, who had had for approximately 3 months an atypical CEM on the right cheek, from which spontaneous extrusion of granular calcified material was noted.…”
A very rare case of calcifying epithelioma of Malherbe (CEM) with a rapid evolution and perforation of the epidermis is reported. Clinical appearance was atypical and did not suggest any diagnosis. Histopathologic examination shows a picture of CEM with some peculiar findings. Furthermore, in the upper dermis there are epithelial strands of shadow cells, partially calcified, tending to come in contact with the perforated epidermis and to be eliminated through it. The acute form of CEM and the mechanism of epidermal perforation in perforating dermatoses are discussed.
“…Perforating pilomatricoma.s sliarc with noii-|)ci foratiiig pilomatricomas, stich clinical fcaltircs as sex of ]3atient, age, and location. Ahliough (he iitimbcr of published cases is still too small for definitive conclusions, the jjrincipal clinical dillcrcnliatingcharacteristics seems to be the color of |jcrforating pilomatricomas which are reddish (8,10), red-blue (II) or blackish-brown (12). These colours ntay be due to the intense inllammatory infiltration invariably observed, especially in the perforated area.…”
A case of perforating pilomatricoma is described. A few published cases have shared the following features: rapid development, reddish exophytic clinical appearance with surface alterations suggestive of perforation, relatively shallow location making contact with the epidermis, and the occurrence of transepithelial elimination phenomena.
“…Although cases with a familial accumulation are on record, there are no certain indications for a hereditary ocurrence [7]. Pilomatricomas are usually solitary tumors, but several lesions in patients have been reported [7, 16, 17]. Multiple pilomatricomas have been observed in association with Gardner’s syndrome [16, 18].…”
We report on 4 elderly patients aged 54–85 years with histopathologically diagnosed pilomatricoma who had been seen in our department from 1993 to 1997. Pilomatricoma is a rather uncommon neoplasm in middle-aged and old patients. It is much better known in children. Here, we clinically studied these 4 cases of pilomatricoma in elderly patients (above 50 years of age) to show the variety of clinical differential diagnosis and discuss the clinicopathological features. The results of the present study indicate that the differential diagnosis of pilomatricoma should also be considered in elderly individuals.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.