Erratum: Imaging of Structural Changes in Endothelial Cells and Thrombus Formation at the Site of FeCl3-Induced Injuries in Mice Cremasteric Arteries[Journal of Atherosclerosis and Thrombosis 807-814]

Different Physical Parameters in the Bonds between Platelet Glycoprotein Ibalpha with von Willebrand factor and with Coagulant Factor XI -Results from the Molecular Dynamic Simulation-

“…[1][2][3][4] They accumulate promptly at vessel injury sites to stop the bleeding. 2,5,6 Under high wall shear rate conditions, initial adhesion of platelets at vessel injury sites is mediated exclusively by their membrane glycoprotein (GP) Iba binding with the A1 domain of von Willebrand factor (VWF) expressed at the site of the injury. [7][8][9][10][11] Stable bindings of GPIba to the VWF could only be detected in specific conditions such as in the presence of ristocetin 12 , botorocetin 13 or with the "gain of function" mutations in either in the GPIba or in the VWF.…”