Erratum: Corrigendum: Identifying polyglutamine protein species in situ that best predict neurodegeneration

Abstract

In the version of this article initially published, the discovery and synthesis of the dafachronic acids was not attributed properly in two instances. On p. 892, the statement "the DAF-9 cytochrome P450 completes the synthesis of the dafachronic-acid hormones 11,13 " should have cited references 11, 13 and 14, and the statement "DAF-9 catalyzes two sequential oxidation steps at the C26 position to generate metabolites that are first hydroxylated and then carboxylated to products named Δ 4 -and Δ 7 -dafachronic acid, respectively 13 " should have cited reference 14 instead of 13. The errors have been corrected in the PDF and HTML versions of this article. In the version of this article initially published, the authors concluded, on the basis of the substantial (approximately five-fold) N1 regioselectivity observed for reactions that form the unsubstituted triazole ureas shown in Figures 1-3, that the major regioisomeric product for the 4-substituted triazole ureas shown in Figures 1 and 3 was also the N1 regioisomer. They have since determined by X-ray crystallography (provided as Supplementary Data Sets 1 and 2) that the N2 regioisomer is the major product for the 4-substituted triazole ureas. The structures have been corrected in the HTML and PDF versions of the article and in the chemical probe