Eradication therapy for peptic ulcer disease in Helicobacter pylori positive patients

Abstract

A 1 to 2 weeks course of H. pylori eradication therapy is an effective treatment for H. pylori positive peptic ulcer disease.

Development and evaluation of evidence-based patient information handbooks about multiple sclerosis immunotherapies

“…In fact, treatment effects in other medical conditions often have similar absolute risk reduction rates between 2 and 10 out of 100. So for example 2 patients out of 100 have a benefit from antibiotic treatment of Helicobacter-associated peptic ulcer disease (Ford et al, 2006). This fits with our earlier work showing that framing critical risk information in a patient-centred way and communicating especially scientific uncertainties is bearable for pwMS (Heesen et al, 2004, Köpke et al, 2018.…”

Development and evaluation of evidence-based patient information handbooks about multiple sclerosis immunotherapies

“…In fact, treatment effects in other medical conditions often have similar absolute risk reduction rates between 2 and 10 out of 100. So for example 2 patients out of 100 have a benefit from antibiotic treatment of Helicobacter-associated peptic ulcer disease (Ford et al, 2006). This fits with our earlier work showing that framing critical risk information in a patient-centred way and communicating especially scientific uncertainties is bearable for pwMS (Heesen et al, 2004, Köpke et al, 2018.…”

Severe and Refractory Peptic Ulcer Disease: The Diagnostic Dilemma

“…In gastric ulcer healing, no significant differences were detected between eradication therapy and ulcer-healing drug (13 trials, 1469 patients; RR = 1.32; 95% CI = 0.92, 1.90). This confirmed that a 1-to 2-week course of H. pylori eradication therapy is an effective treatment for H. pylori-positive peptic ulcer disease (6).…”

Helicobacter pylori status and the extent of gastric atrophy do not affect ulcer healing after endoscopic submucosal dissection

“…Others report that in peptic gastric ulcer healing, no significant differences were detected between eradication therapy and anti-ulcer drug. 18 In the present study we administered PPI for 8 weeks and observed the ulcers 8 weeks after ESD. Because previous studies show that ulcer healing after endoscopic resection needs more than 4 weeks but ≤ 8 weeks, 15,19 there is a possibility that some difference might have been detected if we observed the ulcers more frequently between 4 and 8 weeks after the ESD procedure.…”

Development and evaluation of evidence-based patient information handbooks about multiple sclerosis immunotherapies

“…In fact, treatment effects in other medical conditions often have similar absolute risk reduction rates between 2 and 10 out of 100. So for example 2 patients out of 100 have a benefit from antibiotic treatment of Helicobacter-associated peptic ulcer disease (Ford et al, 2006). This fits with our earlier work showing that framing critical risk information in a patient-centred way and communicating especially scientific uncertainties is bearable for pwMS (Heesen et al, 2004, Köpke et al, 2018.…”

Severe and Refractory Peptic Ulcer Disease: The Diagnostic Dilemma

“…In gastric ulcer healing, no significant differences were detected between eradication therapy and ulcer-healing drug (13 trials, 1469 patients; RR = 1.32; 95% CI = 0.92, 1.90). This confirmed that a 1-to 2-week course of H. pylori eradication therapy is an effective treatment for H. pylori-positive peptic ulcer disease (6).…”

Helicobacter pylori status and the extent of gastric atrophy do not affect ulcer healing after endoscopic submucosal dissection

“…Others report that in peptic gastric ulcer healing, no significant differences were detected between eradication therapy and anti-ulcer drug. 18 In the present study we administered PPI for 8 weeks and observed the ulcers 8 weeks after ESD. Because previous studies show that ulcer healing after endoscopic resection needs more than 4 weeks but ≤ 8 weeks, 15,19 there is a possibility that some difference might have been detected if we observed the ulcers more frequently between 4 and 8 weeks after the ESD procedure.…”

Development and evaluation of evidence-based patient information handbooks about multiple sclerosis immunotherapies

“…In fact, treatment effects in other medical conditions often have similar absolute risk reduction rates between 2 and 10 out of 100. So for example 2 patients out of 100 have a benefit from antibiotic treatment of Helicobacter-associated peptic ulcer disease (Ford et al, 2006). This fits with our earlier work showing that framing critical risk information in a patient-centred way and communicating especially scientific uncertainties is bearable for pwMS (Heesen et al, 2004, Köpke et al, 2018.…”

Severe and Refractory Peptic Ulcer Disease: The Diagnostic Dilemma

“…In gastric ulcer healing, no significant differences were detected between eradication therapy and ulcer-healing drug (13 trials, 1469 patients; RR = 1.32; 95% CI = 0.92, 1.90). This confirmed that a 1-to 2-week course of H. pylori eradication therapy is an effective treatment for H. pylori-positive peptic ulcer disease (6).…”

Helicobacter pylori status and the extent of gastric atrophy do not affect ulcer healing after endoscopic submucosal dissection

“…Others report that in peptic gastric ulcer healing, no significant differences were detected between eradication therapy and anti-ulcer drug. 18 In the present study we administered PPI for 8 weeks and observed the ulcers 8 weeks after ESD. Because previous studies show that ulcer healing after endoscopic resection needs more than 4 weeks but ≤ 8 weeks, 15,19 there is a possibility that some difference might have been detected if we observed the ulcers more frequently between 4 and 8 weeks after the ESD procedure.…”