Journal of Cell Biology volume 216, issue 8, P2295-2304 2017 DOI: 10.1083/jcb.201612165 View full text
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Norfadilah Hamdan, Paraskevi Kritsiligkou, Chris M. Grant

Abstract: ER stress results in widespread aggregation of proteins that are not localized to the ER or are part of the secretory system. Hamdan et al. demonstrate that amorphous and amyloidogenic protein aggregation is an indirect consequence of perturbing ER homeostasis.