volume 23, issue 4, P585-594 2008
DOI: 10.1016/j.jcrc.2008.02.003
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Abstract: The purpose of this review is to introduce differential equations as a simulation tool in the biological and clinical sciences. This modeling technique is very mature and has been a preferred tool of physiologists and bioengineers and of quantitative scientists in general to describe and predict the behavior of complex interacting systems. However, this methodology has not been widely used within clinical medicine due to a lack of familiarity with highly quantitative methods and a greater acquaintance with sta…

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