volume 66, issue 9, P5677-5681 1992
DOI: 10.1128/jvi.66.9.5677-5681.1992
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G Gualandi, E Santolini, E Calef

Abstract: We show here that in a lymphoblastoid cell line Epstein-Barr virus DNA recombines with the human genome. The genetic exchange involves the oriP region of the virus. A junction between viral and human DNA from this line has been cloned and sequenced. The results indicate that the integration of Epstein-Barr virus DNA involves a region of the human genome which contains internal short repetition. An 800-bp probe has been isolated from the human part of the junction. This probe has been used to show that the huma…

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