Epithelioma Cuniculatum

Abstract

A 57-year-old man had a tumor for five years on the plantar surface of his foot. It was treated successfully by surgical curettage. Clinical and pathological features of the tumor are identical and pathological features of the tumor are identical to descriptions of the rare tumor of the foot designated as epithelioma cuniculatum.

DNA dot‐blot hybridization implicates human papillomavirus type 11‐DNA in epithelioma cuniculatum

“…The anatomical distribution of this tumor shows an affinity for the foot in the majority of cases (over 90%) [Kao et al, 1982;Melo et al, 1981;Ratzenhofer, 19821, but other locations such as thumb [Coldiron et al, 19861, hand and lower leg [Elliot et al, 1973;Kao et al, 1982;Klima et al, 19801, and back [Sanchez-Yus et al, 19861 have been reported. Very often, the initial lesion is diagnosed clinically as a wart and is treated as such for many years without success [Brown and Freeman, 1976;Throne, 19721. Histologically, EC is often confused with keratoacanthoma, squamous cell carcinoma, or pseudoepitheliomatous hyperplasia.…”

Epithelioma Cuniculatum, a Verrucous Carcinoma of the Foot

“…Since then, many other cases have been reported [3][4][5][9][10][11][12][13][14][15][16][17], One case was a bilateral tumor [13]. The lesion consists of an exophytic mass located on the sole of the foot, presenting numerous sinuses from which drains malodorous purulent-like material containing keratin debris.…”