Epidermotropic Eccrine Carcinoma

Epidermotropic Eccrine Carcinoma

“…In the case presented these can be excluded on clinical and histological grounds. The patient described shares remarkable similarities with a case reported by Pinkus & Mehregan (1963) under the heading 'Epidermotropic Eccrine Carcinoma'. Extensive warty nodules on a lower limb were present.…”

Metastatic Eccrine Porocarcinoma: A 5.6-Year Follow-up Study of a Patient Treated With a Combined Therapeutic Protocol

“…Microscopically, EP is characterized by an intraepidermal component consisting of nests of poromatous epithelial cells with a significant degree of cytologic atypia that exhibits ductal differentiation and invades the dermis 2,3,9 . Moreover, two characteristic aspects of this tumor, which we were able to evidence in our patient, are lymphovascular invasion and pagetoid extension of the neoplastic cells (epidermotropism) 2,5–7,15–18 . This particular process of metastatic progression, characterized by lymphatic propagation of the tumor cells and final reinvasion of the epidermis, justifies the intense regional spreading of the cutaneous metastases and lymph node invasion, with the subsequent risk of internal metastases 14–16,18,21 …”

Correspondence

“…Venous stasis with secondary complications, such as hyperpigmentation, eczematization, and ulceration, is well known to occur in the legs, the frequent site of stasis dermatitis; 3 however, although varicosity commonly is seen over the abdomen whenever there is portal hypertension, complications of stasis at this site have not been described. 1,2 Hyperpigmentation and dermatitis observed in our patient are due to the extravasation of red blood cells and their degradation, akin to that occurring in the lower limbs.…”