Epidermodysplasia verruciformis associated with severe immunodeficiency, lymphoma, and disseminated molluscum contagiosum

Epidermodysplasia verruciformis-like eruption complicating human immunodeficiency virus infection

“…EV-associated HPV infections were reported in immunodepressed states, such as renal allograft recipients, patients with Hodgkin's disease, systemic lupus erythematosus or malignant neoplasms associated with severe immunodeficiency, and more recently in patients infected with HIV. [5][6][7][8][9][10][11][12]23 It is conceivable that their cellular immunodeficiency predispose patients with acquired immunodeficiency syndrome (AIDS) to cutaneous HPV infections. In vitro NK cell lytic activity was depressed in the two patients evaluated, in clear contrast to studies performed in familial types of EV.…”

“…EV has rarely been observed during acquired immunodeficiency states. [5][6][7][8][9][10][11][12] Only a few cases have been reported in HIV-infected individuals. 11,12 We report here three cases of EV in patients infected with HIV.…”

Acquired epidermodysplasia verruciformis

“…Table I reviews all reported cases of AEV with impaired immunity. [5][6][7][8][9][10][11][12][13][14][15][16][17] Previously reported cases of patients with EV who developed systemic lupus erythematosus 18 or non-Hogkin lymphoma 19 are not included, because these patients had congenital EV followed by the development of systemic diseases affecting their immune system.…”

Systemic lupus erythematosus arising in a patient with epidermodysplasia verruciformis

“…EV has rarely been observed during acquired immunodeficiency states such as renal transplantation, 5 immunodeficiency, lymphoma, disseminated molluscum contagiosum, 8 Bowen's carcinoma, B lymphocytopenia and decreased immune functions, 9 human immunodeficiency virus infection 10 and SLE. 11,12 EV occurs presumably as a result of immunodeficiency or prolonged treatment with corticosteroids.…”