Epidermal growth factor receptor blockers for the treatment of ovarian cancer

Ursolic Acid from <i>Oldenlandia diffusa</i> Induces Apoptosis <i>via</i> Activation of Caspases and Phosphorylation of Glycogen Synthase Kinase 3 Beta in SK-OV-3 Ovarian Cancer Cells

“…In general the treatment consists of a combination of surgery and platinum-based chemotherapy, alone or in combination with paclitaxel. 1) Although recently molecular based therapy developed novel agents, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for ovarian cancer treatment, the adverse effects of EGFR inhibitors including skin and gastrointestinal toxicity of erlotinib are still a hot issue to be overcome.…”

Ursolic Acid from <i>Oldenlandia diffusa</i> Induces Apoptosis <i>via</i> Activation of Caspases and Phosphorylation of Glycogen Synthase Kinase 3 Beta in SK-OV-3 Ovarian Cancer Cells

“…In general the treatment consists of a combination of surgery and platinum-based chemotherapy, alone or in combination with paclitaxel. 1) Although recently molecular based therapy developed novel agents, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for ovarian cancer treatment, the adverse effects of EGFR inhibitors including skin and gastrointestinal toxicity of erlotinib are still a hot issue to be overcome.…”

High serum HTATIP2/TIP30 level in serous ovarian cancer as prognostic or diagnostic marker

“…The onset is often insidious; the symptoms are vague and may mimic other conditions. This may lead to a delay in diagnosis, and currently, three-quarters of women with ovarian cancer are diagnosed when the disease has spread throughout the abdomen [3,4]. …”

Ursolic Acid from <i>Oldenlandia diffusa</i> Induces Apoptosis <i>via</i> Activation of Caspases and Phosphorylation of Glycogen Synthase Kinase 3 Beta in SK-OV-3 Ovarian Cancer Cells

“…In general the treatment consists of a combination of surgery and platinum-based chemotherapy, alone or in combination with paclitaxel. 1) Although recently molecular based therapy developed novel agents, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for ovarian cancer treatment, the adverse effects of EGFR inhibitors including skin and gastrointestinal toxicity of erlotinib are still a hot issue to be overcome.…”

High serum HTATIP2/TIP30 level in serous ovarian cancer as prognostic or diagnostic marker

“…The onset is often insidious; the symptoms are vague and may mimic other conditions. This may lead to a delay in diagnosis, and currently, three-quarters of women with ovarian cancer are diagnosed when the disease has spread throughout the abdomen [3,4]. …”

Ursolic Acid from <i>Oldenlandia diffusa</i> Induces Apoptosis <i>via</i> Activation of Caspases and Phosphorylation of Glycogen Synthase Kinase 3 Beta in SK-OV-3 Ovarian Cancer Cells

“…In general the treatment consists of a combination of surgery and platinum-based chemotherapy, alone or in combination with paclitaxel. 1) Although recently molecular based therapy developed novel agents, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for ovarian cancer treatment, the adverse effects of EGFR inhibitors including skin and gastrointestinal toxicity of erlotinib are still a hot issue to be overcome.…”

High serum HTATIP2/TIP30 level in serous ovarian cancer as prognostic or diagnostic marker

“…The onset is often insidious; the symptoms are vague and may mimic other conditions. This may lead to a delay in diagnosis, and currently, three-quarters of women with ovarian cancer are diagnosed when the disease has spread throughout the abdomen [3,4]. …”