One of the fastest cellular responses following activation of epidermal growth factor receptor is an increase in intracellular Ca 2؉ concentration. This event is attributed to a transient Ca 2؉ release from internal stores and Ca 2؉ entry from extracellular compartment. Store-operated Ca 2؉ channels are defined the channels activated in response to store depletion. In the present study, we determined whether epidermal growth factor activated store-operated Ca 2؉ channels and further, whether depletion of inte…
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