Epidemiology of sebaceous carcinoma of the head and neck: Implications for lymph node management

Abstract

The incidence of nodal disease was higher with eyelid tumors. Sentinel lymph node biopsy can be considered for eyelid tumors, but not for non-eyelid head and neck tumors.

Multifocal Metastasizing Extra-Ocular Facial Sebaceous Carcinoma as Diagnostic Challenge: Case Report and Systematic Review

“…Extra-ocular facial SC is a rather uncommon phenomenon. It is suggested that extra ocular SC has a better prognosis than ocular SC [3,10,15]. Local cutaneous or subcutaneous metastases like in this case report are very uncommon.…”

“…Early lymphogenous and haematogenous metastases are documented in up to 25 % of cases [2,3]. This probability has shown to be less in extra-ocular sites [10]. Accordingly, extra-ocular multifocal facial metastasizing SC is nearly unknown.…”

“…Sentinel lymph node biopsy has been described to be favorable for ocular SC; in positive cases, a lymphadenectomy is advocated [7,11,12]. In extra-ocular head and neck SC a sole observation of regional lymphatic nodes may be reasonable [10].…”

Malignant cutaneous adnexal tumours of the head and neck: an update on management

“…56 It is commonly found on the head and neck and has a propensity to occur on the eyelid in association with the meibomian glands. In a recent review of the surveillance, epidemiology and end results (SEER) database, Tryggvason et al evaluated 1836 cases and identified a male predominance (85%) occurring at an average age of 70.…”

Metastatic Sebaceous Carcinoma– A Rare Presentation

“…Extraorbital sebaceous carcinoma is less aggressive when compared with periorbital because of a reduced tendency for regional metastasis (1.4% for extraorbital vs. 4.4% for periorbital). 2 The parotid gland forms frequent site of origin because of presence of pluripotential cells or ectopic sebaceous glands. Metastasis to parotid gland has also been reported.…”