Epidemiology of Hereditary Coagulation Bleeding Disorders: A 15-Year Experience From Southern Iran

Farjami, Azadeh; Haghpanah, Sezaneh; Arasteh, Peyman; Ardeshiri, Rezvan; Tavoosi, Hakimeh; Zahedi, Zohre; Parand, Shirin; Karimi, Mehran

doi:10.15171/hpr.2017.27

Cited by 6 publications

(7 citation statements)

References 13 publications

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“…The most common rare bleeding disorder in our population was factor VII deficiency (27.9%), followed by fibrinogen deficiency (21.2%). A study conducted in Fars Hemophilia Center, affiliated with the Shiraz University of Medical Sciences, Iran, reported factor VII deficiency as the most frequent rare bleeding disorder, followed by factor X deficiency [14]. Sharma et al [15] re-ported factor X deficiency as the most common rare bleeding disorders, followed by factor XIII and factor VII deficiencies.…”

Section: Discussionmentioning

confidence: 99%

Rare bleeding disorders: spectrum of disease and clinical manifestations in the Pakistani population

et al. 2020

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Background Rare inherited coagulation factor deficiencies constitute an important group of bleeding disorders. A higher frequency of these disorders is seen in areas of high consanguinity. Our aim was to study the prevalence and spectrum of rare inherited bleeding disorders, characterize the severity of the deficiencies, identify different clinical manifestations, and evaluate different treatments provided. Methods This cross-sectional study was conducted in the Department of Haematology, Armed Forces Institute of Pathology Rawalpindi, between January 2014 and December 2018. A detailed history was taken, and an examination was performed. The signs and symptoms were noted, and the patients were diagnosed on the basis of a coagulation profile. The disease severity was assessed using factor assays. Results Among 2,516 patients with suspected coagulation disorders, 774 (30.8%) had an inherited bleeding disorder. Of the 774 patients, 165 (21.3%) had a rare bleeding disorder; 91 (55.2%) of them were males, and 74 (44.9%) were females, with a male-to-female ratio of 1.2:1. The median patient age was 9 years 3 months. The most common disorder was factor VII deficiency (46 patients, 27.9%). The most common clinical presentation was bruising in 102 (61.8%) and gum bleeding in 91 (55.2%) patients. Conclusion The most common rare bleeding disorder in our population is factor VII deficiency. The prevalence of these bleeding disorders is high in our population due to a high number of consanguineous marriages.

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Section: Discussionmentioning

confidence: 99%

Rare bleeding disorders: spectrum of disease and clinical manifestations in the Pakistani population

et al. 2020

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“…The present developmental study was conducted in 2016 in a library and used the sectional format in 3 steps. First, data was collected using a checklist based on Iranian Diabetes Association criteria and other library studies, [14][15][16][17] The checklist was given to the study participants to complete the second step. It contained 52 open-and closed-ended questions in 5 parts.…”

Section: Methodsmentioning

confidence: 99%

Design and Evaluation of a Mobile-Based Application for Patients With Type 2 Diabetes: Case Study of Shariati Hospital in Tehran, Iran

et al. 2018

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Background: With regard to the particularly high prevalence, cost, and number of disabilities associated with diabetes, increasing patients’ knowledge and skills for managing the disease can help minimize the risks of complications. Objective: The present study aimed to design and evaluate a mobile-based application with which patients with type 2 diabetes can increase their knowledge of and skills for managing their disease. Methods: The current developmental-applied study was conducted in 2016 in a library and used a 2-step sectional format. The research population comprised 15 physicians and endocrinologists working in medical centers associated with Tehran University of Medical Sciences and 20 physicians and patients. Based on the library study, a checklist was designed and then distributed among participants. Their responses were analyzed using SPSS software version 20. Results: The data was divided into 4 main sections: identity information (patient demographics), clinical information, education curriculum related to diabetes management, and program requirements for diabetes management, which consisted of 52 subsets. The evaluation of the system by doctors and patients showed that the system has high capabilities. Conclusion: Mobile-based programs can help diabetics control blood glucose levels, reduce diabetes complications, and promote overall health.

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“…Another study done in Iran shows that the prevalence rates of hepatitis B and C were 0.5% and 11.5%, respectively, among 619 patients with heredity bleeding disorders [13]. Studies from some neighboring Arabic countries reported an HCV infection rate of 29.4% to 79% among multi-transfused patients [14,15] .…”

Section: Ijbpas February 2019 8(2)mentioning

confidence: 99%

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IJBPAS

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Background: Viral hepatitis places a heavy burden on the health care. Large number of patient with bleeding disorders has chronic hepatitis C infection, while few are chronic carriers of hepatitis B virus.Aims of study: evaluate the prevalence of HBV, HCV infection among patient with Von Willebrand disease and to find factors that associated with the chance of getting the infection. Materials and methods: A cross sectional study was conducted on 145 patients with vonWillebrand disease who registered in Hereditary Bleeding Disorders Unit at Medical City, Baghdad, during period between first of December 2017 to the 31st of July 2018. SPSS version 24 was used in statistical analysis. Descriptive statistics were presented as frequency and percentages. Chi-square test for association. P ≤ 0.05 considered as a significant association.Results: Out of total 145 patients, 16 patients were HCV antibody positive with a prevalence of 11% , None of the patients had HBV. There is a significant statistical association between the patient age and hepatitis C viral infection, (20%) of patients ages between 20-29 years were

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Epidemiology of Hereditary Coagulation Bleeding Disorders: A 15-Year Experience From Southern Iran

Cited by 6 publications

References 13 publications

Rare bleeding disorders: spectrum of disease and clinical manifestations in the Pakistani population

Rare bleeding disorders: spectrum of disease and clinical manifestations in the Pakistani population

Design and Evaluation of a Mobile-Based Application for Patients With Type 2 Diabetes: Case Study of Shariati Hospital in Tehran, Iran

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