Epidemiology of Delayed Union of Long Bones

Mehmood, Moin; Deshp, Sanjay; Khan, Shehtaj; Singh, Pradeep K; Patil, B G; Rathi, Romil

doi:10.4172/2167-1222.1000370

Cited by 4 publications

(4 citation statements)

References 19 publications

(17 reference statements)

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“…25 26,27 In this series nailing resulted in better union rates. Delayed union was noted up to 18.5% in Fong et al and 18.95% in Mehmood et al 28,29 Factors which influenced delayed union in this review was grade of injury. In a study by Westgeest et al with a study of 736 subjects concluded that higher Gustilo grade fractures were associated with non-union and delayed union.…”

Section: Discussionmentioning

confidence: 60%

Recapitulation of primary nailing in open diaphyseal fractures of tibia

et al. 2019

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Tibia fractures are the commonest long bone fracture, most commonly resulting from high velocity injury. We investigated whether primary nailing in open tibia fractures were producing satisfactory outcomes and we compared the outcomes in terms of fracture union and rates of infection. We identified 202 citations related to our searches from our key words, out of which 89 were original articles, which were eligible and others were case reports and review articles. We found 4 from these references which had the parallel inclusion criteria and were reviewed. All 4 studies had almost similar time period for the fracture union. Infection rates in this study were directly related to the severity of the grade of injury, which were commonly experienced in grade III injuries. In conclusion, our analysis had no significant difference in postoperative healing duration, implant failure rates, postoperative infection and secondary operation rates in primary nailing for open tibia fractures.

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Section: Discussionmentioning

confidence: 60%

Recapitulation of primary nailing in open diaphyseal fractures of tibia

et al. 2019

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“…Large bone defects are difficult to manage and can result in nonunions (Gomez‐Barrena et al, 2015; Mehmood, Deshpande, Khan, Singh, & Patil, 2017). In this case, the bone defect resulted from the removal of abnormal and infected bone that occurred after trauma.…”

Section: Discussionmentioning

confidence: 99%

Treatment of a large osseous defect in a feline tarsus using a stem cell‐seeded custom implant

Fitzpatrick¹,

Black²,

Choucroun³

et al. 2020

J Tissue Eng Regen Med

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The aim of this study is to describe the treatment of an infected segmental bone defect in a cat using a novel, custom-designed titanium implant seeded with adiposederived stem cells (AdMSCs) to facilitate osseous ingrowth and preserve limb function. Large bone defects occur secondary to trauma, infection, or neoplasia and often result in amputation. We established a novel autologous AdMSC-impregnated trabecular metal spacer made using 3D printing, to bridge the distal tibia and metatarsal bones in the left pelvic limb of a cat that had previously undergone right pelvic limb amputation. Six months postoperatively, there was radiographic evidence of bone growth and implant integration. A titanium spacer seeded with AdMSCs successfully encouraged bone ingrowth in a large defect site and successfully preserved limb function. However, further studies are needed to justify the use of differentiated stem cell impregnated mesh as a framework to bridge large bone defects.

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“…16.7% of the patients in this study had delayed union, which is comparable to Katie fong, et al [39] . Who had 18.5% and Moin Mehmood et al [40] . Had 18.95%.…”

Section: Factors Influencing Unionmentioning

confidence: 98%

Clinical and radiological outcome of intramedullary nailing in grade I and II (Gustilo-Anderson) compound diaphyseal fractures of tibia

Pradeepkumar¹,

Chandrasekaran²,

Dhiyanesh³

et al. 2019

Int. J. Orthop. Sci.

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Background: The effectiveness of primary intramedullary nailing in open diaphyseal fractures in tibia is still controversial and the available literature is unclear. We conducted a study to evaluate the functional and radiological results of primary reamed intramedullary nailing in the management of open diaphyseal tibia fractures of Grade I & II (Gustilo-Anderson). Patients and Methods: This is a prospective study, in which 30 Grade I & II open diaphyseal fractures of tibia who came to our hospital EMS fulfilling Inclusion & Exclusion criteria were included in this study. This study was done from the period of Jan 2017 to Sept 2018. They were evaluated on each follow up clinically by Klemn & Borner Score, radiologically by RUST score and the rate of infection was evaluated using Southampton Score. Results: The average rate of union in this study was 28.5 weeks. 5 patients developed delayed union out which 4 patients underwent dynamization. There was a significant improvement in all the scores compared to previously availed method of fixation. Factors that influenced infections and delayed union in this study were Grade of injury, Diabetes and the habit of smoking. Conclusion:Results of our study shared that, primary Intramedullary Nailing in Grade I & II open Diaphyseal fractures of tibia showed earlier fracture union when compared to the historical data on modalities of fixation with lesser infection and non-union rates.

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Epidemiology of Delayed Union of Long Bones

Abstract: Aim: To study the epidemiology of delayed union of long bones.

Cited by 4 publications

References 19 publications

Recapitulation of primary nailing in open diaphyseal fractures of tibia

Recapitulation of primary nailing in open diaphyseal fractures of tibia

Treatment of a large osseous defect in a feline tarsus using a stem cell‐seeded custom implant

Clinical and radiological outcome of intramedullary nailing in grade I and II (Gustilo-Anderson) compound diaphyseal fractures of tibia

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