Epidemiological and clinical characteristics of Trypanosoma cruzi infection in dogs (Canis lupus familiaris) from a Chagas Disease-Endemic Urban Area in Colombia

Jaimes-Dueñez, Jeiczon; Jiménez-Leaño, Ángela; Esteban-Mendoza, M.Victoria; Moreno-Salcedo, Lucas Andres; Triana-Chávez, Omar; Cantillo-Barraza, Omar

doi:10.1016/j.prevetmed.2020.105093

Cited by 11 publications

(9 citation statements)

References 35 publications

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“…Blood samples derived from 213 dogs originating from the AMB and collected under the frame of previous studies carried out in our research group were screened for the presence of T. evansi DNA (Jaimes-Dueñez et al, 2020). The inclusion criteria for pets, epidemiological information, and collection and processing of samples were carried out following Jaimes-Dueñez et al, (2020). AMB is a Colombian conurbation, located in the department of Santander, in the Río de Oro valley.…”

Section: Animal Enrollmentmentioning

confidence: 99%

“…using the Woo test. The procedures were performed according to Jaimes-Dueñez et al, (2020). The motility of trypanosomes was evaluated following the procedures described by Woo (1970).…”

Section: Parasitological Diagnosismentioning

confidence: 99%

“…PCR controls were obtained from canine blood samples previously diagnosed as positive and negative for T. evansi by (Jaimes-Dueñez et al, 2017a). Finally, PCR inhibitors were evaluated as previously reported (Jaimes-Dueñez et al, 2020). Samples in which this housekeeping gene could not be amplified were excluded from the analysis.…”

Section: Dna-based Testsmentioning

confidence: 99%

“…Canine trypanosomiasis is a disease complex caused by two main Trypanosoma species: Trypanosoma (Schizotrypanum) cruzi producing the Chagas disease (American form) and Trypanosoma (Trypanozoon) evansi producing the surra (African form) (Desquesnes et al, 2013). In America, dogs are considered the main reservoir for the transmission of T. cruzi infection in domestic areas, with most animals presenting a subclinical infection, with few cases developing hematological alterations and significant cardiac abnormalities that rarely cause fatality (Crisante et al, 2006;Jaimes-Dueñez et al, 2020). In contrast, dogs naturally infected with T. evansi show acute and severe clinical signs (case-fatality rate > 90%) (Echeverria et al, 2019;Filgueiras et al, 2019;Jaimes-Dueñez et al, 2017a), that discard the role of this host as an important reservoir of the parasite.…”

Section: Introductionmentioning

confidence: 99%

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Understanding the Epidemiology of Trypanosoma Evansi Infection in Dogs (Canis lupus familiaris) from Urban Areas of Colombia

Jaimes-Dueñez¹,

Jiménez-Leaño²,

Montenegro-Ayala³

et al. 2022

American Journal of Animal and Veterinary Sciences

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Trypanosoma evansi is a protozoan parasite that is the causative agent of the animal disease known as "surra", which affects a wide variety of wild and domestic mammals including humans. This study aimed to evaluate the molecular point prevalence and clinic-epidemiological traits of T. evansi infection in dogs from municipalities of the Metropolitan Area of Bucaramanga (MAB), Santander, Colombia. From 2019 and 2020, a crosssectional study in four municipalities of MAB was carried out to evaluate the above features in 213 healthy dogs from these cities. Molecular analysis using the primer ESAG/6 and ESAG/7, showed a T. evansi frequency of 1.8% (CI 95% = 0.04-3.68%), while Woo test didn't detect positive animals. A high prevalence of infection was detected in Piedecuesta (10.53%) and Bucaramanga (1.65%), apparently negative animals were detected in Giron and Florida Blanca. Clinical characteristics revealed that all positive animals (4/4) showed low Mean Corpuscular Hemoglobin (MCH) and (3/4) low Mean Corpuscular Volume (MCV), and one animal had a moderate fever with prolonged capillary refill time. The epidemiological characteristics showed that all animals received mixed food, (3/4) came from low socioeconomic areas, and (2/4) from neighborhoods without weekly garbage collection. In conclusion, molecular methods detected a considerable prevalence of animals chronically infected by T. evansi in MAB, with more frequency in neighborhoods of a low socio-economic level where animals have more risk of oral transmission. These results should be considered during urban control programs of surra in MAB.

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Section: Animal Enrollmentmentioning

confidence: 99%

“…using the Woo test. The procedures were performed according to Jaimes-Dueñez et al, (2020). The motility of trypanosomes was evaluated following the procedures described by Woo (1970).…”

Section: Parasitological Diagnosismentioning

confidence: 99%

Section: Dna-based Testsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Understanding the Epidemiology of Trypanosoma Evansi Infection in Dogs (Canis lupus familiaris) from Urban Areas of Colombia

Jaimes-Dueñez¹,

Jiménez-Leaño²,

Montenegro-Ayala³

et al. 2022

American Journal of Animal and Veterinary Sciences

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“…The role of cats and dogs is particularly important as infection sources for the vector. 14 , 15 Given the proximity between the houses in this urban environment, the mobility and habits of these hosts might contribute to the dispersion of the parasite in the area. Although birds are refractory to T. cruzi infection, they can maintain triatomine colonies.…”

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confidence: 99%

Urban infestation by Triatoma infestans (Hemiptera: Reduviidae), an overlooked phenomena for Chagas disease in Argentina

Provecho

Fernández

Salva

et al. 2021

Mem. Inst. Oswaldo Cruz

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Vector-borne transmission of Chagas disease in urban areas of Argentina has been an overlooked phenomena. We conducted the first comprehensive cross-sectional study of domestic infestation with Triatoma infestans and vector infection with Trypanosoma cruzi in a metropolitan area of San Juan, Argentina. Our results document the occurrence of T. infestans infected with T. cruzi in human sleeping quarters. In this urban setting, we also show that infestation was associated with construction materials, the presence of chickens, cats and a large number of dogs that can provide blood meals for the vector. Our findings reveal new challenges for vectorial control agencies.

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Trypanosomiasis

Hamer¹,

Saunders²,

Snowden³

et al. 2021

Greene's Infectious Diseases of the Dog and Cat

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Epidemiological and clinical characteristics of Trypanosoma cruzi infection in dogs (Canis lupus familiaris) from a Chagas Disease-Endemic Urban Area in Colombia

Cited by 11 publications

References 35 publications

Understanding the Epidemiology of Trypanosoma Evansi Infection in Dogs (Canis lupus familiaris) from Urban Areas of Colombia

Understanding the Epidemiology of Trypanosoma Evansi Infection in Dogs (Canis lupus familiaris) from Urban Areas of Colombia

Urban infestation by Triatoma infestans (Hemiptera: Reduviidae), an overlooked phenomena for Chagas disease in Argentina

Trypanosomiasis

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