Epidemic Methicillin-Gentamicin–Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit

Outbreaks of infection with methicillin-resistantStaphylococcus aureuson neonatal and burns units of a new hospital

“…In common with our experience, others have found closure of neonatal units impossible because of the lack of alternative ventilation facilities [26,28], and cohorting of colonized babies and staff has been found to cause considerable disruption [17,24,33]. Bathing with hexachlorophane was highly effective in neonatal outbreaks of the 'hospital staphylococcus' [39] and has been used in recent MRSA outbreaks [28,33,34]. However, worries over hexachlorophane's toxicity limit its use, and there is little experience with mupirocin in neonatal outbreaks.…”

A five year outbreak of methicillin-susceptible Staphylococcus aureus phage type 53,85 in a regional neonatal unit

“…1, interventions F and G) after limiting intra-unit transfer and introduction of cohorting or barrier nursing of infected\colonised babies. Transfer within the unit may facilitate efficient use of specialist cots and nursing care, but excessive movement can be counter-productive, because of the impact on infection control measures [30,31]. We were unable to confirm staff shortages as a significant factor in this outbreak.…”

Outbreak of invasive disease caused by methicillin-resistant Staphylococcus aureus in neonates and prevalence in the neonatal intensive care unit

“…ported that 18.8% of the affected neonates were infected and 6.3% had bloodstream infections. Reboli et al (7) noted much higher proportions of patients with infections in general (42%) and with bloodstream infections in particular (18%). Campbell et al (15) reported that 33% of the neonates affected in an MRSA outbreak were infected and all had bacteremia.…”