1999
DOI: 10.1001/archderm.135.7.804
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Eosinophilic, Polymorphic, and Pruritic Eruption Associated With Radiotherapy

Abstract: Objective: To characterize the epidemiological, clinical, and histopathological features of patients with cancer who develop widespread polymorphic and pruritic skin lesions following radiotherapy.Patients, Design, and Interventions: During phase 1, epidemiological and clinical features of 103 patients with cancer, 83 treated with radiotherapy (71 women and 12 men) and 20 controls who did not undergo radiotherapy (16 women and 4 men), were explored during 3 months (October 1995 to January 1996. During phase 2… Show more

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Cited by 48 publications
(66 citation statements)
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“…A group of patients shows cutaneous lesions that develop after deep radiation therapy, especially in patients with brain tumors in association with anticonvulsant therapy. In our and Rueda et al's [1] experience, such lesions occur in 0.02-1.2% of all treated patients. Clinically, they resemble erythema multiforme, although they do not fulfill all its clinical and/or histological criteria [3,4].…”
supporting
confidence: 54%
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“…A group of patients shows cutaneous lesions that develop after deep radiation therapy, especially in patients with brain tumors in association with anticonvulsant therapy. In our and Rueda et al's [1] experience, such lesions occur in 0.02-1.2% of all treated patients. Clinically, they resemble erythema multiforme, although they do not fulfill all its clinical and/or histological criteria [3,4].…”
supporting
confidence: 54%
“…Despite its frequency, this syndrome has been reported only in two articles, and the majority of the patients had genital cancers [1,2]. We report an additional case in a patient with esophageal carcinoma.…”
mentioning
confidence: 80%
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“…Les manifestations cliniques de la radiodermite aiguë sont l'érythème, l'oedème, la douleur, la desquamation, l'ulcéra-tion et le suintement [2]. Les autres complications cutanées aiguës de la radiothérapie sont le phénomène recall, la « comédo-réaction », l'atteinte des phanères, des éruptions variées [3]. Les effets secondaires tardifs surviennent et s'aggravent progressivement.…”
Section: Effets De La Radiothérapieunclassified