Eosinophilic Granuloma of Bone With Cutaneous Manifestations

Curtis, Arthur C.

doi:10.1001/archderm.1947.01520060072008

Cited by 48 publications

(6 citation statements)

References 3 publications

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“…This is of considerable interest, for the child presented with a flexural eruption and, although the lesions progressed to affect the trunk and scalp, there was never any involvement of the face such as is usually seen in cases of infantile eczema. A similar affection of the skin with the same distribution and reddish-brown scaly appearance is known to occur in cases of Hand-Schuller-Christian disease (Merritt and Paige, 1933;Lane and Smith, 1939;Curtis and Cawley, 1947), but has not, so far as we know, been reported in cases of Letterer-Siwe disease other than in the one described by Reye. At necropsy there was a remarkable similarity between our two cases.…”

Section: Discussionsupporting

confidence: 56%

Two Cases of Hand-Schuller-Christian Disease in Infancy

Nash¹,

Cavanagh²

1952

Archives of Disease in Childhood

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The diversity of the clinical features of HandSchuller-Christian disease is well recognized. Although it is a disorder affecting chiefly young children, its occurrence in the first year of life is rare.The two cases presented here indicate that the form of the disease found in infants tends to be more rapid in its course and the lesions more widespread than in older children. At October 25, 1944, at the age of 9 months. Her parents and an elder brother and sister were quite well, and the pregnancy and labour had been normal. There was some difficulty with feeding until the age of 6 weeks when breast feeding was replaced by a cow's milk mixture. At the age of 3 weeks her mother noticed that there were three red spots on the roof of the mouth. The significance of this observation is not known and no further mention of it is made in the case notes.At the age of 4 months (five months before admission) the right side of the face became swollen. At first the child was thought to be suffering from mumps but shortly afterwards she was admitted to a hospital near her home, and the cervical lymph nodes were incised. The only material obtained at the operation was said to be congealed blood. The lymph nodes on both sides of the neck increased in size and the child's general condition deteriorated rapidly.On admission she was extremely ill, pale, dyspnoeic and cyanosed. The temperature was 960 F., the pulse 154 per minute and respirations 86 per minute. Large subcutaneous masses were found on both sides of the neck. They were firm, smooth, and fixed to the deep structures. The percussion note at both posterior lung bases was impaired and coarse crepitations were heard in all areas. The abdomen was very distended, the liver just palpable, and the spleen was firm and enlarged to three fingersbreadths (2 in.) below the costal margin.

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Section: Discussionsupporting

confidence: 56%

Two Cases of Hand-Schuller-Christian Disease in Infancy

Nash¹,

Cavanagh²

1952

Archives of Disease in Childhood

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“…There were no true cutaneous lesions of a seborrhoeic or eczematous nature. Skin lesions of a similar nature have been described in Hand-Schtiller-Christian disease by Herzenberg (1928), by Lane and Smith (1939), and more recently by Curtis and Cawley (1947) in a case of eosinophilic granuloma of bone. Such lesions are frequent but not invariable accompaniments of systemic reticuloendothelial granuloma.…”

Section: Discussionsupporting

confidence: 55%

Reticulondothelial Granuloma: A Review with a Report of a Case of Letterer-Siwe Disease

Claireaux¹,

Lewis²

1950

Archives of Disease in Childhood

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“…Simple urinary specific gravity determinations were compatible with diabetes insipidus, the only item of signifi¬ cance of the numerous chemical, hémato¬ logie, and sérologie determinations. 7. Response to Treatment.-Our experi¬ ence in this case has covered a wide range of therapeutic agents and modalities.…”

Section: Commentmentioning

confidence: 99%

Histiocytosis X (Granulomatous Reticuloendotheliosis)

Bender¹

1958

AMA Arch Derm

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Eosinophilic Granuloma of Bone With Cutaneous Manifestations

Cited by 48 publications

References 3 publications

Two Cases of Hand-Schuller-Christian Disease in Infancy

Two Cases of Hand-Schuller-Christian Disease in Infancy

Reticulondothelial Granuloma: A Review with a Report of a Case of Letterer-Siwe Disease

Histiocytosis X (Granulomatous Reticuloendotheliosis)

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