Eosinophilic Cystitis Induced by Bacillus Calmette-Guerin (BCG) Intravesical Instillation

Hidoussi, A.; Slama, A.; Jaidane, Mehdi; Zakhama, W.; Youssef, Adel Ben; Sorba, N. Ben; Mosbah, A

doi:10.1016/j.urology.2007.07.032

Cited by 17 publications

(18 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We found 4 patients who had HES and EC including the present patient and 14 EC patients who had no etiology and an eosinophil count as described in the report [3,4,5,6,7,8,9,10,11,12,13,14,15]. Of the 14 patients reported as EC, 5 had an eosinophil count of ≥1,500/μl on at least one occasion without apparent cause of eosinophilia, which suggests that these patients had HES (table 1).…”

Section: Resultsmentioning

confidence: 62%

Eosinophilic Cystitis Presented as a Manifestation of Hypereosinophilic Syndrome: A Case Report and Review of the Literature

et al. 2013

View full text Add to dashboard Cite

Background: Hypereosinophilic syndrome (HES) is a group of disorders marked by the sustained overproduction of eosinophils, in which eosinophilic infiltration and inflammatory substance release cause damage to multiple organs. Eosinophilic cystitis (EC) is an inflammatory disorder caused by eosinophilic infiltration of the bladder wall. Although EC is often associated with eosinophilia, it has been rarely reported as a manifestation of HES. We report a case of EC as a primary manifestation of HES. The patient was a 27-year-old male with a history of complete intracardiac repair of tetralogy of Fallot who presented with an acute onset of dysuria accompanied by eosinophilia (7.5 × 10³/µl, 60% of white blood cells). Ultrasonography and MRI of the bladder showed a bladder mass, a biopsy of which revealed eosinophilic infiltration and degranulation. Methods: We performed a literature search in PubMed from 2001 to 2012 to find patients with EC who may have had HES. Results: There were 4 patients with HES who had EC including the present case. Of 14 patients reported as EC in whom the eosinophil count was described, 5 had eosinophils of ≥1,500/µl. None of the 5 patients had secondary causes for eosinophilia. Of the 9 patients with definite or probable HES, 7 patients (78%) were male and 5 patients (56%) showed a concomitant eosinophilic gastrointestinal disorder. Conclusion: HES may not be uncommon as the cause of EC. Thorough evaluation and close monitoring are warranted in EC patients with elevated eosinophils.

show abstract

Section: Resultsmentioning

confidence: 62%

Eosinophilic Cystitis Presented as a Manifestation of Hypereosinophilic Syndrome: A Case Report and Review of the Literature

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Some cases of EC were most likely caused by medication (penicillin,25 Coumadin,13 BCG,15 levetiracetam,4 dimethyl sulfoxide and Mitomycin-C2 13). The most common causative and associative factors to EC are listed in table 3.…”

Section: Discussionmentioning

confidence: 99%

Eosinophilic cystitis: three cases, and a review over 10 years

2014

View full text Add to dashboard Cite

SUMMARYEosinophilic cystitis (EC) is a rare disease. We describe three cases, where presentations of the disease are similar. To highlight probable causes of the disease, symptoms, clinical findings and treatment modalities, we reviewed 56 cases over a 10-year period. The most common symptoms were frequency, dysuria, urgency, pain and haematuria. Common clinical findings were presence of bladder mass, peripheral eosinophilia and thickened bladder wall. A variety of medical treatments were used, most frequently steroids, antibiotics and antihistamines. Recurrence occurred in patients on tapering or discontinuing prednisone, among other reasons. There is no consensus about the treatment of EC, but In light of our findings in this review, the treatment of choice in our department will be tapered prednisone over 6-8 weeks in combination with antihistamine.

show abstract

“…Although benign, this disease is at times clinically aggressive and locally invasive [ 3 , 4 ]. The proliferative nature of the IEPT histopathology has led some doctors to recommend open surgical removal or complete transurethral resection for definitive treatment [ 5 , 6 ]. We report a case of IEPT of the bladder which regressed with prednisone administration alone.…”

Section: Discussionmentioning

confidence: 99%

Glucocorticosteroid-sensitive inflammatory eosinophilic pseudotumor of the bladder in an adolescent: a case report

Liu

Gao

et al. 2009

J Med Case Reports

View full text Add to dashboard Cite

IntroductionInflammatory eosinophilic pseudotumor of the bladder is a rare inflammatory bladder disease. The etiology and pathophysiology of this condition are still unclear. Few case reports have described inflammatory eosinophilic pseudotumor of the bladder in adults or children. Although benign, this disease is occasionally clinically aggressive and locally invasive, thus open surgical removal or complete transurethral resection is recommended.Case presentationWe present the case of a biopsy-proven inflammatory eosinophilic pseudotumor of the bladder in a previously healthy 16-year-old male adolescent with 2-month history of frequent micturition and dysuria with no significant apparent causative factors. The tumor regressed after a 6-week course of glucocorticosteroids.ConclusionTo the best of our knowledge, our case is a rare case of inflammatory eosinophilic pseudotumor of the bladder treated with complete conservative management. Due to its glucocorticosteroid-sensitive nature, we postulate that this disease belongs to a subgroup of eosinophilic disorders.

show abstract

Eosinophilic Cystitis Induced by Bacillus Calmette-Guerin (BCG) Intravesical Instillation

Cited by 17 publications

References 7 publications

Eosinophilic Cystitis Presented as a Manifestation of Hypereosinophilic Syndrome: A Case Report and Review of the Literature

Eosinophilic Cystitis Presented as a Manifestation of Hypereosinophilic Syndrome: A Case Report and Review of the Literature

Eosinophilic cystitis: three cases, and a review over 10 years

Glucocorticosteroid-sensitive inflammatory eosinophilic pseudotumor of the bladder in an adolescent: a case report

Contact Info

Product

Resources

About